Life satisfaction is widely thought important—so important that many identify it with, or think it central to, happiness. But three problems undermine its significance. Most importantly, our evaluations of our lives are inherently arbitrary, so that life satisfaction’s importance as a verdict on one’s life is dubious. Second, most people appear not to have, or need, well-defined attitudes of li...

In this paper we address the two-sided regulated random walk defined by the relation XN(t + 1)= min(N,max(0,XN(t)+ A(t+1))) where (A(t); t 1) is a sequence of i.i.d r.v’s with integer values such that A(t) −1,E{A} = 0 and E{rA}<+∞ for an r > 1. Denoting by πN its stationary distribution, FN(x)= πN([0,Nx]) and G(x) the d.f of a uniform r.v on [0,1]. It is shown that 0 < limN‖FN −G‖p limN‖FN −G‖p...

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There have been a number of major advances in the treatment of systemic lupus erythematosus and we are now in the era of biologic therapies for this multisystem autoimmune disorder. There has been a greater awareness of the toxicities of the traditional therapies including the recognition that the doses of corticosteroids used in the past have been excessive, resulting in unacceptable toxicitie...