نتایج جستجو برای: water maze

تعداد نتایج: 557571  

Journal: :Physiology & behavior 2005
Angela M Gouirand Leslie Matuszewich

Exposure to chronic stress can affect cognitive processes in a complex manner depending upon the intensity and duration of the stressors. The current study investigated the effects of chronic unpredictable stress (CUS), a procedure thought to use moderate stressors, on acquisition of and performance in the Morris Water Maze (MWM). Separate behavioral tests were also used to determine whether th...

2015
Ji Hyun Kim Qian Wang Ji Myung Choi Sanghyun Lee Eun Ju Cho

BACKGROUND/OBJECTIVES Alzheimer's disease (AD) is characterized by deficits in memory and cognitive functions. The accumulation of amyloid beta peptide (Aβ) and oxidative stress in the brain are the most common causes of AD. MATERIALS/METHODS Caffeic acid (CA) is an active phenolic compound that has a variety of pharmacological actions. We studied the protective abilities of CA in an Aβ25-35-...

Journal: :Brain : a journal of neurology 2009
Seralynne D Vann

Mammillary body atrophy is present in a number of neurological conditions and recent clinical findings highlight the importance of these nuclei for memory. While most accounts of diencephalic amnesia emphasize the functional importance of the hippocampal projections to the mammillary bodies, the present study tested the importance of the other major input to the mammillary bodies, the projectio...

Journal: :iranian journal of radiation research 0
y.a. zorkina vp serbsky national research center for social and forensic psychiatry, department of basic and applied neurobiology, kropotkinskiy side street 23, 119034, moscow, russian federation e.a. zubkov vp serbsky national research center for social and forensic psychiatry, department of basic and applied neurobiology, kropotkinskiy side street 23, 119034, moscow, russian federation z.i. storozheva vp serbsky national research center for social and forensic psychiatry, department of basic and applied neurobiology, kropotkinskiy side street 23, 119034, moscow, russian federation g.e. gorlachev burdenko neurosurgery institute rams, department of radiology and radiosurgery, 4th tverskaya-yamskaya st. 16, 125047, moscow, russian federation a.v. golanov burdenko neurosurgery institute rams, department of radiology and radiosurgery, 4th tverskaya-yamskaya st. 16, 125047, moscow, russian federation v.p. chekhonin vp serbsky national research center for social and forensic psychiatry, department of basic and applied neurobiology, kropotkinskiy side street 23, 119034, moscow, russian federation

background: ionizing radiation causes cognitive impairment in adult brain. however, the effects of various irradiation protocols with fractionated fixed total dose on hippocampal function have not yet been studied. materials and methods: fractionated whole brain irradiation with a total dose of 36 gy was performed according to the following protocols: 2gy-18 fractions (2gy*18), 4gy-9 fraction (...

Abbas Alimoradian, Amir Hossein Saeedi, Hossein Miladi , Mehdi Sadegh , Mohammad Zahiri, Saeed Ghasemi,

Background and Aim: Learning and memory defect occurs following chronic diabetes with uncontrolled blood glucose. Ginkgo leaf extract improves brain blood flow. Also it contains antioxidant components and has shown beneficial effects in neurological diseases. In this study we investigated the effects of Ginkgo leaf extract on spatial memory impairment and hippocampal neuronal loss caused by dia...

A.V. Golanov, E.A. Zubkov, G.E. Gorlachev, V.P. Chekhonin, Y.A. Zorkina, Z.I. Storozheva,

Background: Ionizing radiation causes cognitive impairment in adult brain. However, the effects of various irradiation protocols with fractionated fixed total dose on hippocampal function have not yet been studied. Materials and Methods: Fractionated whole brain irradiation with a total dose of 36 Gy was performed according to the following protocols: 2Gy-18 fractions (2Gy*18), 4Gy-9 fraction (...

Journal: :Physiological research 2005
S Gönenç N Uysal O Açikgöz B M Kayatekin A Sönmez M Kiray I Aksu B Güleçer A Topçu I Semin

Melatonin has recently been suggested as an antioxidant that may protect neurons from oxidative stress. Acute ethanol administration produces both lipid peroxidation as an indicator of oxidative stress in the brain and impairs water-maze performance in spatial learning and memory tasks. The present study investigated the effect of melatonin against ethanol-induced oxidative stress and spatial m...

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