1. Foreign body giant cells may be produced in vitro by the addition of foreign objects such as lycopodium spores and cotton fibers to cultures of chick embryo spleen. 2. These giant cells are formed by the fusion of large mononuclear wandering cells, probably endothelial cells and pulp cells. Connective tissue cells do not take part in their formation. 3. The large giant cells sometimes seen s...

A 15 years old patient was taken to the operative room for an explorative laparotomy due to abdominal pain and a pelvic spleen at preoperative computed tomography: was pointed out the absence of all splenic ligamentous attachments and short gastric vessels with a consequently dislocation of a bigger and congested spleen in the pelvis. This organ, wrapped in the omentum, was in a serious ischemi...

We present the case of an eighteen years old woman with the maturational disorder who went to the emergency area because of abdominal pain, focused on the left iliac fossa, fever and vomiting, since four days ago. The blood test showed 15.000 leukocytes, with 81% of neutrophils and PCR, 154. On the physical exploration, a mass on the left quadrant was noticed and positive peritonism signs. The ...

A 55-year-old woman presented with recurrent abdominal pain, a lump in her abdomen, and vomiting. In the previous 10 years, she required multiple hospital admissions for pain. Examination revealed pallor and a lump (20 cm 15 cm) extending from left hypochondrium to left iliac region. Labs showed hemoglobin 7.8 g/dL, platelet count 5,100 cells/mm, and serum protein/ albumin 6.7/3.4 g/dL; the res...

BACKGROUND AND OBJECTIVES Laparoscopic transperitoneal left adrenalectomy (LTLA) has become the standard treatment for adrenal masses<6 cm. LTLA involves the dissection of splenic suspensory ligaments, which replicates their congenital absence or weakening, present in cases of wandering spleen (WS). WS is a rare condition in which the spleen migrates from the left upper quadrant to a more cauda...

Previous clinical attempts to correct genetic deficiencies such as hemophilia or Gaucher disease by transplantation of allogeneic spleen were associated with aggressive graft versus host disease, mediated by mature T cells derived from the donor spleen. We show that a fetal pig spleen harvested at the embryonic day 42 stage, before the appearance of T cells, exhibited optimal growth potential u...