Fibroadenoma of the vulva is an uncommon lesion. It has been suggested that they originate from vulvar mammary like other glands. A few examples of benign and malignant vulvar tumors arising from such glands have been reported. A 32-year-old woman was referred with a subcutaneous mass at the vulva. The patient treated by simple excisional surgery with adequate peripheral margin. Histologic...

We report hereby two cases of fluorescence-guided surgical resection with Indocyanine green in vulvo-vaginal neoplasia. The first case was a 86-year old patient who had high-grade squamous intraepithelial lesion the left small lip and on vulvar fork. After incomplete surgery, second vulvectomy performed ICG injected intravenously to determine intraoperatively margins. At final pathologic examin...

BACKGROUND The association between lichen sclerosus and vulvar squamous cell carcinoma (VSCC) has long been recognized, but large epidemiologic studies are lacking. METHODS Data of women diagnosed with vulvar pathology in the Netherlands were retrieved from the Dutch Pathology Registry. All vulvar pathology reports of this historical cohort were reviewed to construct a research database, incl...

Zoon vulvitis or vulvitis chronica plasmacellularis is a rare, chronic benign inflammation of the vulvar mucosa, diagnosed histologically, with variable therapeutic responses. It is important to be diagnosed because it mimics the presentation of other genital conditions, such as lichen planus and squamous cell carcinoma, which require specific treatment. We report a case of a female patient wit...

Background: Basal cell carcinoma (BCC) is the most common malignant neoplasm in humans, accounted for at least 75% of non-melanoma skin cancers. The BCCs are directly related to intense exposure to ultraviolet radiation, being diagnosed preferentially in body areas with larger sunlight exposure. However, these tumors may appear in areas which are normally covered from ultraviolet light. Vulvar ...

BACKGROUND Malignant tumors arising from the vulva account for only 0.6 % of all cancers in female patients. The predominant histologic type, representing about 90 % of these malignancies, is squamous cell carcinoma. Eccrine porocarcinoma is a rare malignant tumor arising from sweat glands. The incidence of eccrine porocarcinoma is estimated at 0.005-0.01 % of all cutaneous tumors. To the best ...

Primary breast cancer fairly infrequently occurs in ectopic breast tissue, and primary ectopic breast cancer of the vulva is particularly rare. Only 26 cases have been published in the English-language literature, and there has been no report of primary breast carcinoma of the vulva in Japan. We report a rare case of primary ectopic breast cancer of the vulva that was treated with local excisio...