BACKGROUND Suction blister grafting is a useful modality of treatment of patients with resistant and stable vitiligo. However, there have been no detailed studies to find out the best donor site for blister formation. METHODS The study was conducted between the period of October 2004 and February 2005 in the dermatology department at a tertiary care center. Nine patients with vitiligo (focal ...

Vitiligo is a common autoimmune disease of the skin that results in disfiguring white spots. There are no Food and Drug Administration (FDA)-approved treatments, and current treatments are time-consuming, expensive, and of low efficacy. We sought to identify new treatments for vitiligo, and first considered repurposed medications because of the availability of safety data and expedited regulato...

BACKGROUND Generalized vitiligo is an autoimmune disease of skin pigmentation that is associated with increased prevalence of other autoimmune diseases, particularly autoimmune thyroid disease (AITD; principally Hashimoto's disease and Graves' disease), both in vitiligo patients and their close relatives, suggesting a heritable predisposition involving, in part, shared susceptibility genes. S...

introduction: the hallmark of vitiligo is the disappearance of melanocytes from the skin due to an as yet unidentified mechanism. the presence of melanocytes in the auditory apparatus suggests that this system could possibly be affected by vitiligo, which targets the melanocytes of the whole body and not just the skin.the purpose of this study was to assess the incidence of auditory alterations...

An overview of unconventional therapies for vitiligo is presented. Some herbal compounds may be considered as valid therapeutic tools for the treatment of vitiligo.

BACKGROUND Current vitiligo therapies require many months of treatment and often result in disappointing outcomes. Treatment with a 308-nm excimer laser has shown promising results in patients with vitiligo. OBJECTIVE This controlled prospective trial studied the effectiveness of the 308-nm excimer laser for treating vitiligo in Asians. METHODS Thirty-four patients (14 males and 20 females)...

We are in an era of modern medicine that is defined by rapid change. Scientists are accumulating and analyzing scores of genomic data, however, the majority of data being accumulated on vitiligo has not been appropriately archived or systemized for analysis (Alikhan et al, 2011; Spritz, 2011). The pathogenensis of vitiligo is multifactorial, and includes three main factors: genetic, immunologic...

Vol. 27, No. 1, 2015 107 Received March 12, 2014, Revised April 4, 2014, Accepted for publication April 9, 2014 Corresponding author: Ozge Mine Orenay, Department of Dermatology, Faculty of Medicine, Turgut Ozal University, Alparslan Turkes Caddesi No. 57, Ankara 06510, Turkey. Tel: +90-312-203-5257, Fax: +90-312-221-3670, E-mail: [email protected] This is an Open Access article distributed ...

Psoriasis and vitiligo are very common skin disorders that may have a profound impact upon the affected individuals; the etiology of both diseases includes genetic factors and triggers, which could be endogenous or exogenous. Two groups of children population consisting of 153 patients suffering from skin disorder (65 with vitiligo and 88 with psoriasis) have been examined at the Department of ...

BACKGROUND Vitiligo is an acquired and progressive hypomelanotic disease that manifests as circumscribed depigmented patches on the skin. Although the precise mechanism remains to be elucidated, an imbalance of the oxidant/antioxidant system has been proposed as an important etiologic mechanism. OBJECTIVE The objective of this study was to evaluate the oxidant/antioxidant status of vitiligo p...