BACKGROUND/AIMS To determine the impact of prosthetic replacement of the ocular surface ecosystem (PROSE) treatment at 5 years. METHODS Retrospective review of clinical, manufacturing and quality databases at the Boston Foundation for Sight. RESULTS 121 patients who completed treatment and had 5-year follow-up data were identified from a cohort of patients (n=199) seen in consultation for P...

OBJECTIVE We wished to determine the effectiveness of horizontal rectus tenotomy in changing the nystagmus of patients with congenital nystagmus and, secondarily, how their visual function changed. DESIGN This was a prospective, noncomparative, interventional case series. PARTICIPANTS Ten adult patients with varied associated sensory defects and oculographic subtypes of congenital nystagmus...

PURPOSE To assess the effect of ranibizumab treatment for neovascular age-related macular degeneration (nvAMD) on patients' preferences and vision-related quality of life (VRQoL) in a routine clinical setting. METHODS 55 treatment naïve patients were examined before and after the initial upload of three monthly injections of 0.5 mg ranibizumab. VRQoL was assessed using a Rasch-adjusted NEI-VF...

Purpose: To evaluate anxiety, depression status, and vision-related quality of life (QoL) in patients with age-related macular degeneration (AMD) during the early phase COVID-19 pandemic. Results: There was no statistically significant difference HADS-A HADS-D between AMD group controls (p<0.05) When were assigned to two distinct groups according binocular visual acuity, proportion above HAD...

OBJECTIVE To examine whether women with premature ovarian failure (POF) have abnormal findings in ocular surface or tear parameters and whether they report symptoms of ocular discomfort compared with age-matched controls. METHODS Sixty-five patients with POF and 36 age-matched healthy controls were examined for signs and symptoms of dry eye. The Ocular Surface Disease Index questionnaire and ...

OBJECTIVES The aims of this analysis were to confirm the UK results in other countries and to explore the possibility of subscales of the 25-Item Macular disease Dependent Quality of Life (MacDQoL) questionnaire. METHODS Two clinical studies were pooled. Principal components analyses (Varimax) were conducted on baseline data from each country and from all combined. Factorial structures were c...

Purpose To examine the effect of a home visit-based visual rehabilitation intervention on: (1) self-reported visual function and (2) depression, wellbeing, loneliness, adjustment to visual loss, and generic health-related quality of life. Methods In an exploratory, assessor-masked, individually randomized, single-center controlled trial, 67 participants (age: 75.22 ± 16.21 years) with low vis...

BACKGROUND The importance of evaluating the outcomes of health care from the standpoint of the patient is now widely recognized. The purpose of this study is to develop and test a Japanese version of the National Eye Institute Visual Function Questionnaire (NEI VFQ-25). METHODS A Japanese version was developed with a previously standardized method. The questionnaire and optional items were co...

BACKGROUND Economic viability of treatments for primary open-angle glaucoma (POAG) should be assessed objectively to prioritise health care interventions. This study aims to identify the methods for eliciting utility values (UVs) most sensitive to differences in visual field and visual functioning in patients with POAG. As a secondary objective, the dimensions of generic health-related and visi...

OBJECTIVES To assess the effectiveness of a self-management program for age-related macular degeneration (AMD) in reducing depressive symptoms. DESIGN Analysis of 6-month follow-up for a subset of participants in a randomized, controlled trial who were clinically depressed at baseline. SETTING University ophthalmology clinic. PARTICIPANTS Thirty-two depressed older adult volunteers (mean ...