Background: Abnormal myocardial loading can contribute to left ventricular (LV) mechanical dyssynchrony in patients with end-stage renal disease (ESRD) and may be a factor contributing to the high incidence of cardiac deaths in these patients. The study aims to evaluate the possible presence of LV dyssynchrony in ESRD patients, and acute effect of hemodialysis (HD) on LV synchronicity using tis...

Background The amount and location of left ventricular (LV) mechanical dyssynchrony affects an individual’s ability to respond positively to cardiac resynchronization therapy (CRT) [Bax et al JACC 2005]. By using high temporal resolution short-axis cines, it is possible to derive radial motion curves throughout the LV. These radial motion curves can be used to create maps showing dyssynchronous...

INTRODUCTION AND OBJECTIVES Permanent His-bundle pacing is effective in patients with supra-Hisian atrioventricular block. We report our experience in patients with infra-Hisian atrioventricular block. METHODS The study involved selected patients referred for syncope and intraventricular conduction disturbance, infra-Hisian atrioventricular block, with left ventricular dyssynchrony and no cor...

BACKGROUND Right ventricular pacing may be deleterious in patients with left ventricular dysfunction, but in patients with normal function the impact of this stimulation triggering clinically relevant ventricular dysfunction is not fully established. OBJECTIVES To evaluate the clinical, echocardiographic findings of patients with previously normal left ventricular function underwent implantat...

AIMS Plasma B-type natriuretic peptide (BNP) is an emerging biomarker in heart failure. In this setting, the extent of left ventricular (LV) dyssynchrony contributes to exercise symptoms. Whether exercise-induced changes in LV dyssynchrony might be a trigger of BNP release has never been investigated. METHODS AND RESULTS Fifty-seven patients with systolic LV dysfunction underwent quantitative...

Cardiac resynchronization is an established treatment modality in patients with heart failure NYHA class III-IV on optimal medical treatment, QRS duration of at least 120-130 ms and ejection fraction <35%. Nevertheless, a proportion of patients, up to 20-30%, are considered non-responders as they are not improved by cardiac resynchronization therapy (CRT). This report describes a 63-year-old pa...

BACKGROUND Left ventricular (LV) dyssynchrony is a prevalent feature in heart failure (HF) patients. The current study aimed to evaluate the prevalence of inter and intraventricular dyssynchrony in HF patients with regard to the QRS duration and etiology. METHODS The available data on the tissue Doppler imaging (TDI) of 230 patients with refractory HF were analyzed. The patients were divided ...