BACKGROUND AND PURPOSE Aspiration of secretions containing bacterial pathogens into the lower respiratory tract is the main cause of ventilator-associated pneumonia. Endotracheal tubes with subglottic secretion drainage can potentially reduce this and, therefore, the incidence of ventilator-associated pneumonia. New evidence on subglottic secretion drainage as a preventive measure for ventilato...

Mucopolysaccharidosis type II (MPS II) is an X-linked recessive disorder characterized by a deficiency of the enzyme iduronate-2-sulfatase leading to a multisystem involvement by tissue accumulation of glycosaminoglycans heparan and dermatan sulfate. We report a case of a 9-year-old boy diagnosed with mucopolysaccharidosis type II at 4 years of age, classified as severe variant. He presented ne...

objective a 4-month-old female with osteogenesis imperfecta (oi) type ii was admitted in picu of our center due to severe respiratory distress and fever with a diagnosis of severe pneumonia, and mechanical ventilation was initiated. due to severe hypotonia, ncv and emg were performed, and spinal muscular atrophy (sma) type i was diagnosed.

Received 10/14/2004; revised 3/14/2005; accepted 3/17/2005. For correspondence or reprints contact: Zen-Kong Dai, M.D., Department of Pediatrics, Kaohsiung Municipal Hsiao-Kang Hospital. 483 Shan-Ming Road, Hsiao-Kang District, Kaohsiung 812, Taiwan. Tel: (886)7-3121101 ext. 7153, Fax: (886)7-3117521, E-mail: [email protected] Background: In this study, we enrolled pediatric cases with history of...

BACKGROUND To see if early tracheostomy (fifth day) reduces duration of mechanical ventilation, ICU stay, incidence of pneumonia and mortality in comparison with prolonged intubation (PI) in patients with head injury. METHODS Patients were prospectively included in this study if they met the following criteria: isolated head injury, Glasgow coma scale (GCS) score < or =8 on first and fifth da...

More than three-quarters of deaths related to major burns are a consequence of infection, which is frequently ventilator associated pneumonia (VAP). A retrospective study was performed, over a five-year period, of ventilated children with major burns. 92 patients were included in the study; their mean age was 3.5 years and their mean total body surface area burn was 30%. 62% of the patients sus...

BACKGROUND Streptococcus pneumoniae is the main cause of community-acquired pneumonia in adults. AIM To describe baseline characteristics, risk factors and clinical outcomes of adult patients hospitalized with pneumococcal pneumonia. MATERIAL AND METHODS Prospective study of adult patients admitted for a community acquired pneumonia in a clinical hospital. Immune deficient patients and thos...

The aim. Based on the study of effect invasive mechanical ventilation and NIV in CPAP mode pathomorphosis lung damage patients with HRF caused by SARS-nCoV-2 deaths intensive care unit (ICU), determine safest method respiratory support.&#x0D; Materials methods. included morphological material from 20 (COVID-19) who died ICU. Group 1 received non-invasive through a face mask (n=10), group 2 - un...

BACKGROUND Legionella species, Mycoplasma pneumoniae, and Chlamydia pneumoniae are recognized as important causes of pneumonia in high-income countries, but their significance in middle-income countries, such as Thailand, is unknown. METHODS Population-based surveillance identified inpatient 3489 cases of clinically-defined pneumonia in a rural Thai province for 1 year. Patients who had a che...