نتایج جستجو برای: vasodilators

تعداد نتایج: 1976  

Journal: :Japanese journal of pharmacology 1985
S Komori M Ishii K Hashimoto

Antiarrhythmic effects of intravenous coronary vasodilators (verapamil, diltiazem, bepridil, trimetazidine and nicorandil) were evaluated using two canine ventricular arrhythmia models (halothane-adrenaline arrhythmia and digitalis arrhythmia), and the minimum effective plasma concentrations of the drugs were determined for each arrhythmia model. Verapamil (0.1 mg/kg), diltiazem (0.1 mg/kg), be...

Journal: :British heart journal 1993
C Houde D J Bohn R M Freedom M Rabinovitch

OBJECTIVE To describe the demographic and haemodynamic variables of children presenting with primary pulmonary hypertension or pulmonary hypertension appearing or persisting after surgical correction of congenital heart defects and to assess the acute effect of vasodilator drugs on their pulmonary vascular bed. DESIGN Retrospective review. SETTING Paediatric cardiology department and intens...

Journal: :COPD 2009
Charles D Burger

The possibility that pulmonary hypertension (PH) may develop in patients with chronic obstructive pulmonary disease (COPD) is well established, but prevalence data vary. The current World Health Organization clinical classification includes COPD in diagnostic group III: PH associated with disorders of the respiratory system or hypoxemia. The National Institute of Health defines PH as a mean pul...

2014
Babak Sharif-kashani Ali Hamraghani Jamshid Salamzadeh Mohammad Abbasi Nazari Majid Malekmohammad Neda Behzadnia Fanak Fahimi

Pulmonary hypertension (PH) is an important cause of heart failure in chronic obstructive pulmonary disease (COPD). The pro brain natriuretic peptide N-terminal (NT-proBNP) has been suggested as a noninvasive marker to evaluate ventricular function. However, there is no evidence to support the use of NT-proBNP in monitoring the benefits of vasodilators in COPD induced PH. Thus, we used NT-proBN...

Journal: :Journal of the American College of Cardiology 1984

Journal: :Hypertension 2012
Hongliang Li David C Kem Sean Reim Muneer Khan Megan Vanderlinde-Wood Caitlin Zillner Daniel Collier Campbell Liles Michael A Hill Madeleine W Cunningham Christopher E Aston Xichun Yu

Agonistic autoantibodies to the β-adrenergic and muscarinic receptors are a novel investigative and therapeutic target for certain orthostatic disorders. We have identified the presence of autoantibodies to β2-adrenergic and/or M3 muscarinic receptors by ELISA in 75% (15 of 20) of patients with significant orthostatic hypotension. Purified serum IgG from all 20 of the patients and 10 healthy co...

Journal: :Internal medicine 2008
Girolamo Catapano-Minotti Andrea Corsonello Giovanni Guadalupi Rosalia Spani Raffaele Antonelli-Incalzi

We present a case of scleroderma complicated by severe pulmonary hypertension. The use of a three-drug (bosentan, iloprost, and sildenafil) approach contributed to significant improvement of both the clinical conditions and the pulmonary hemodynamics. Combining three pulmonary vasodilators with different mechanisms of action could benefit patients with severe pulmonary hypertension resistant to...

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