Introduction: The phenomenon of basic vaccine hesitancy in parents is the biggest challenge faced byhealth workers global era currently. This study aimed to analyze relationship between perceivedbenefits, perceived barriers, and knowledge about vaccines towards among anti provaccinecommunities on social media Facebook.Methods: used a cross-sectional design. sample was 150 members anti-vaccineco...

abstract        background and objective: aluminum salts are among the most common useful additive compounds in preparation of human and animal vaccines. aluminum phosphate and aluminum hydroxide are two additives that show good immunoadjuvant effects with many antigens. aluminum-containing vaccines lead to a better and longer immune response compared to adjuvant-lacking vaccines. the chromogen...

OBJECTIVE To determine how the withdrawal from the market of the rotavirus vaccine has affected physicians' trust in vaccine safety mechanisms, future adherence to vaccine recommendations, and willingness to use a new rotavirus vaccine. DESIGN National survey mailed to 1228 randomly selected pediatricians and family physicians. MAIN OUTCOME MEASURES Confidence in vaccine safety mechanisms w...

Brucellosis is a bacterial zoonotic disease affecting several mammalian species that is transmitted to humans by direct or indirect contact with infected animals or their products. In cattle, brucellosis is almost invariably caused by Brucella abortus. Live, attenuated Brucella vaccines are commonly used to prevent illness in cattle, but can cause abortions in pregnant animals. It is, therefore...

RNA viruses are capable of rapid spread and severe or potentially lethal disease in both animals and humans. The development of reverse genetics systems for manipulation and study of RNA virus genomes has provided platforms for designing and optimizing viral mutants for vaccine development. Here, we review the impact of RNA virus reverse genetics systems on past and current efforts to design ef...

Until now, design of the annual influenza vaccine has relied on phylogenetic or whole-sequence comparisons of the viral coat proteins hemagglutinin and neuraminidase, with vaccine effectiveness assumed to correlate monotonically to the vaccine-influenza sequence difference. We use a theory from statistical mechanics to quantify the non-monotonic immune response that results from antigenic drift...