Cell death in Drosophila is regulated by many of the same signals that control apoptosis in mammalian systems. For all the three major cell death pathways that have been described in humans, homologous components have been identified in Drosophila. Here we report that distinct pathways mediate UV-induced apoptosis at different developmental stages in the Drosophila embryo. In midstage embryos, ...

This paper presents an electronic travel aid for blind people to navigate safely and quickly, an obstacle detection system using UVC camera based visual navigation has been considered. The proposed system detects the obstacles up to 300 cm via sonar and sends feedback in form of beep sound to inform the person about its location. In addition to this, an UVC webcam is connected to 32 bit ARM mic...

Understanding how to recover fully functional and transcriptionally active chromatin when its integrity has been challenged by genotoxic stress is a critical issue. Here, by investigating how chromatin dynamics regulate transcriptional activity in response to DNA damage in human cells, we identify a pathway involving the histone chaperone histone regulator A (HIRA) to promote transcription rest...

The lifespan of an acute brain slice is approximately 6-12 hours, limiting potential experimentation time. We have designed a new recovery incubation system capable of extending their lifespan to more than 36 hours. This system controls the temperature of the incubated artificial cerebral spinal fluid (aCSF) while continuously passing the fluid through a UVC filtration system and simultaneously...

The nucleolus has long been considered to be a pure ribosome factory. However, over the last two decades it became clear that the nucleolus is involved in numerous other functions besides ribosome biogenesis. Our experiments indicate that the activity of RNA polymerase I (Pol I) transcription monitors the integrity of the DNA and influences the response to nucleolar stress as well as the rate o...

The relationship between turbidity (T) and ultraviolet C (UVC) disinfection is still not clearly understood, as well no attention has been paid to the contribution of natural organic matter (NOM). present work assessed influence particulate NOM on UVC efficiency in terms E. coli MS2 removal at bench collimated beam (CB) flow-UVC systems, both laboratory field (Colombia). reactor was installed p...

Since early 2003, the Koninklijke Bibliotheek (KB) maintains a deposit service called e-Depot, based on the IBM product DIAS (Digital Information and Archiving System). By using this service, the KB has developed a workflow for archiving electronic publications and has implemented the other parts of the infrastructure in which the deposit system is embedded. Now that the infrastructure is in pl...

Every country in the globe has been profoundly affected by coronavirus epidemic, and these countries are struggling with how to clean areas quickly effectively. This project aims contribute fight against spread of quickly, safely, effectively cleaning medical clinics. Regular disinfection might reassure people increase their confidence lessened risk communicable diseases. Robots that use ultrav...

With the widespread of novel coronavirus (SARS-CoV-2), inactivation bacteria and viruses using ultraviolet (UV) light has been reevaluated. However, there are many applications where safety to human body itself effect questioned, is a movement review UV-C guidelines (Global Lighting Association, Position Statement on Germicidal Irradiation SAFETY GUIDELINES, 2020). Since Minamata Convention Mer...