BACKGROUND Uterine arteriovenous malformations are rare, potentially life-threatening, vascular anomalies. CASE We report a case of a large arteriovenous malformation diagnosed during pregnancy that was successfully treated with bilateral uterine artery embolization at 20 weeks of gestation during an ongoing pregnancy. The procedure was uncomplicated, did not result in any fetal heart-rate ch...

BACKGROUND We assessed the results and impact of blockage of utero-ovarian anastomoses (UOA) on clinical outcome in women treated by laparoscopic uterine artery occlusion for uterine fibroids. METHODS Between 2004 and 2005, we prospectively analyzed the clinical data for 23 laparoscopic uterine artery occlusion cases combined with blockage of utero-ovarian anastomoses (Group A) and 67 laparos...

The uterine vasculature undergoes profound adaptations in response to pregnancy. Augmentation of endothelial vasodilator function and reduced smooth muscle reactivity are factors contributing to uterine artery adaptation and are critical for adequate placental perfusion. The peptide hormone relaxin has an important role in mediating the normal maternal renal vascular adaptations during pregnanc...

In mammalian pregnancy, maternal cardiovascular adaptations must match the requirements of the growing fetus(es), and respond to physiologic and pathologic conditions. Such adaptations are particularly demanding for mammals bearing large-litter pregnancies, with their inherent conflict between the interests of each individual fetus and the welfare of the entire progeny. The mouse is the most co...

Characteristics of the uterine and umbilical artery blood flow patterns are indirect measures of uteroplacental circulation. We examined whether uterine and umbilical artery resistance indices are influenced by maternal demographic and lifestyle characteristics, track from the second trimester to the third, and are associated with the risk of pregnancy complications. This analysis was embedded ...

BACKGROUND We aimed to evaluate the effect of the levonorgestrel-releasing intrauterine system (LNG-IUS) on the uterine vasculature and the endometrium. METHODS The study was a prospective controlled study evaluating the local effects of LNG-IUS compared with the copper intrauterine device (IUD). Forty-seven women carrying LNG-IUS (group A) were compared with 35 women carrying copper IUD in a...

BACKGROUND The pharmacological management of early pregnancy loss reduced substantially the need for dilation and curettage. However, prognostic markers of successful outcome were not established. Thus the major purpose of this study was to determine the sensitivity and specificity of the uterine artery pulsatility (PI) and resistance (RI) indices to detect early pregnancy loss patients requiri...

Objectives: To study the uterine artery resistance and pulsation indices during the mid luteal phase in patients with history of unexplained recurrent pregnancy loss and the effects of the nitric oxide donor isosorbid mononitrite on these indices. Study Design: A cross-section, controlled observational study. Setting: Benha University Hospital, Egypt. July 2009 to July 2010. Subjects and Method...

The aim of this study was to evaluate the effect of nifedipine, drug that inhibits uterine contractions, on parameters of blood flow in the middle cerebral artery of the fetus and of the maternal placental circulation. Flow in the middle cerebral artery of the fetus, umbilical artery and uterine arteries of pregnant women and their fetuses with pre-term labor were analysed. The study included 7...