PURPOSE Up to 50% of urinary tract infections (UTIs) in young children are missed in primary care. Urine culture is essential for diagnosis, but urine collection is often difficult. Our aim was to derive and internally validate a 2-step clinical rule using (1) symptoms and signs to select children for urine collection; and (2) symptoms, signs, and dipstick testing to guide antibiotic treatment....

OBJECTIVES Women presenting in primary care with symptoms suggestive of uncomplicated urinary tract infection (UTI) are commonly managed without urine culture. We therefore do not know how successful general practitioners (GPs) are at targeting antibiotic treatment to women who would have had a microbiologically confirmed UTI, or at avoiding antibiotics in those who would have had a negative cu...

Results: A total of 5321 laboratory requests comprising 4506 malaria parasites (MP), 414 urine microscopy, culture and sensitivity (urine m/c/s), and 410 blood culture were made, processed and reports generated. Of these, 1040 (19.6%) were not collected or delivered to the requesting physician. Urine m/c/s with 37.9% (157/414) accounted for the highest test-specific non-collected reports, close...

Children with urinary tract abnormalities are susceptible to bacterial urinary infection (UTI); fungal infection, although rare, is reported to be increasing. Here, we describe a seven month-old male infant with posterior urethral valves who had developed both bacterial and fungal (Candidal) urinary tract infections. Direct and culture examinations of urine sample confirmed urinary tract candid...

BACKGROUND Tuberculosis is the most common cause of death among patients with HIV infection living in tuberculosis endemic countries, but many cases are not diagnosed pre-mortem. We assessed the test characteristics of urinary lipoarabinomannan (LAM) and predictors of mortality among HIV-associated tuberculosis suspects in Tanzania. METHODS We prospectively enrolled hospitalized HIV-infected ...