Both the literature and personal investigations (Popchristov, 1957) indicate beyond any doubt that the relative percentage of urethritis and vaginitis due to Trichomonas vaginalis rises with increased rates of non-gonococcal genital infections. Of 278 patients with non-gonococcal urethritis and colpitis, and 102 patients with gonorrhoea seen at the Dispensary of the Institute for Skin and Vener...

A FEW isolated facts have stimulated the writing of this review. The chief are (i) The finding by some workers that an antigen made from the urethral discharge of patients with " Waelsch urethritis" acts like Frei antigen in cases of lymphogranuloma inguinale. (2) The discovery by Gay-Prieto, Findlay, Miyagawa and others of the bodies now believed to be the virus of lymphogranuloma inguinale. (...

The relapse rate and its causation have been studied in 378 fresh cases of nonspecific urethritis. None of these cases had had treatment for the condition prior to attending this Centre; The diagnosis was established by finding, within seven to twenty-one days of exposure, a hazy urine with numerous pus threads and a mucopurulent· discharge which on staining by Gram's method showed numerous pus...

Mycoplasma genitalium is a cause of nongonococcal urethritis, particularly in patients not infected with Chlamydia trachomatis. A quantitative 5' nuclease assay (TaqMan PCR) was developed and validated. The assay detected a fragment of the MgPa adhesin gene by use of a TaqMan MGB (minor groove binder) probe and included an internal processing control to detect PCR inhibition. Urethral swab spec...

Quantitative determinations of U. urealyticum and M. hominis have been performed in 164 men with non-gonococcal urethritis (NGU) and 597 patients with chronic prostatitis. Evidence is provided that U. urealyticum plays an etiologic role in 29.3 percent of patients with non-gonococcal urethritis. Mixed infections of C. trachomatis and U. urealyticum, in high numbers, do occur in 11 percent of NG...

A recent study and review of the literature (Ford, 1960) provided no support for the view that the usual strains of genital pleuropneumonia-like organisms (PPLU) were a cause of non-gonococcal urethritis (NGU). It was noted, however, that Shepard (1956, 1957, 1960) had isolated morphologically distinct T-strain PPLO from the genital tract of patients with NGU, and that he believed these T-strai...

Of the chlamydia species that can cause infections in humans, C. trachomatis is responsible for lower urinary tract diseases in men and women. C. trachomatis infections are prevalent worldwide, but current research is focused on females, with the burden of disease and infertility sequelae considered to be a predominantly female problem. However, a role for this pathogen in the development of ma...

In a prospective study of unselected, female patients attending a sexually transmitted disease clinic one in eight patients would have been errouneously declared free of infection in the absence of a chlamydial culture service. Chlamydia trachomatis is now accepted as a causative organism of non-specific urethritis and post-gonococcal urethritis in men and non-specific genital infection in wome...