BACKGROUND Diabetes mellitus is a massive, growing, silent epidemic that has the potential to cripple health services in all parts of the world. Currently, a diagnosis of diabetes is achieved by evaluating plasma glucose levels. Saliva offers some distinctive advantages. Whole saliva can be collected non-invasively and by individuals with limited training. The present study was aimed to estimat...

BACKGROUND Candida albicans is the most common opportunistic fungal species in the oral cavity. Various factors associated with C. albicans infection have been evaluated so far. In some studies, the relationship between the blood group antigens and C. albicans has been discussed. The aim of this study was to assess mean C. albicans colony counts in the saliva of healthy subjects and its relatio...

BACKGROUND To determine the prevalence of xerostomia and hyposalivation in Haemodialysis (HD) patients, to clarify risk factors, assess patient's quality of life, and to establish a possible correlation among interdialytic weight gain (IDWG) and xerostomia. MATERIAL AND METHODS This study was performed on a group of 50 HD patients. Data were collected using a questionnaire containing demograp...

Aim: Oral cancer is a major health problem in India associated with significant morbidity and mortality. Due to the absence of truly specific symptoms, the early diagnosis of oral cancer is quite challenging. Aberrant glycosylation of cell surface glycoconjugates is an important feature of malignant changes. Abnormal glycosylation in cancer leads to formation of altered glycoconjugates such as ...

BACKGROUND Oral lichen planus (OLP) is a chronic inflammatory mucosal disease of unknown aetiology. Recently, increased oxidative stress has been implicated in the pathogenesis of various diseases. The aim of this study was to evaluate the total antioxidant capacity (TAC) and lipid peroxidation level, in the saliva of patients with OLP. METHOD Thirty patients with OLP (15 men, 15 women; mean ...

BACKGROUND Detection of cancer at an early stage is of utmost importance to decrease the morbidity and mortality of the disease. Apart from the conventional biopsy, non-invasive methods like analysis of serum and saliva may provide cost-effective approach for screening a large population. Tumor markers are a major part of secondary prevention and thus, the detection of malignancies. The aim of ...

We describe a direct radioimmunoassay for cortisol in 10-microliter volumes of parotid saliva or whole saliva. Binding proteins are absent from these fluids, as demonstrated by the excellent correlation between results for samples assayed directly and by a comparison procedure involving extraction with 1,2-dichloroethane. The direct assay is specific, precise, and had a lower limit of sensitivi...

background and aims. lysozyme and lactoferrin are salivary proteins which play an important role in innate defense mechanisms against bacteria. this study investigated the association of salivary lysozyme and lactoferrin concentrations with early childhood caries (ecc). materials and methods. this study was carried out on 42 healthy children (age range, 36 to 71 months), of whom 21 were caries ...

  Background: Oral lichen planus (OLP) has been classified as a pre-malignant condition. Matrix metalloproteinase-13 (MMP-13) or collagenase-3 may play a key role in cancer development. The aim of this study was to compare serum and saliva MMP-13 between patients with oral lichen planus (OLP) and oral squamous cell carcinoma (OSCC).   Methods : This cross sectional study was performed on 30 pat...