The current analysis aimed to evaluate the role of tranexamic acid in preventing seroma formation after ventral hernia repair. This cross-sectional study was conducted at Bakhtawar Amin Trust Hospital Multan from 20th Jan 2020 2021. included patients diagnosed with Those cirrhosis, strangled hernias, uncontrolled diabetes mellitus, and bleeding disorders were excluded. volume measured using a v...

As described in detail in other chapters of this volume, conditions with excessive bleeding, as are seen with uterine rupture, placenta accreta, abruption and uterine atony, often require intensive resuscitation with blood components and coagulation factors. In such circumstances, blood transfusion may be life-saving, but on occasion involves exposing the patient to additional risks. Over the y...

Injection sclerotherapy is now the accepted first line treatment for bleeding oesophageal varices, although it is associated with an impressive list of rare complications. The main problem concerns the strategy for uncontrollable or recurrent bleeding. Patients with uncontrolled bleeding may be referred for surgery after considerable blood loss and are then extremely difficult to assess. The ef...

bnormal uterine bleeding occurs in 9 to 14 percent of women between menarche and menopause, significantly impacting quality of life and imposing financial burden. The etiologies and treatments for abnormal uterine bleeding over the reproductive years are best understood in the context of normal menstrual physiology. A normal cycle starts when pituitary follicle-stimulating hormone induces ovari...

BACKGROUND Uncontrolled haemorrhage is still the leading cause of preventable death after trauma and the primary focus of any treatment strategy should be related to early detection and control of blood loss including haemostasis. METHODS For assessing management practices across six European level I trauma centres with academic interest and research in the field of coagulopathy an online sur...

BACKGROUND Despite hemostat use, uncontrolled surgical bleeding is prevalent. Drawbacks of current hemostats include limitations with efficacy on first attempt and suboptimal ease-of-use. Evarrest® is a novel fibrin sealant patch that has demonstrated high hemostatic efficacy compared with standard of care across bleeding severities. The objective of this study was to conduct a hospital cost an...

BACKGROUND Uncontrolled bleeding is a leading cause of death in trauma. Two randomized, placebo-controlled, double-blind trials (one in blunt trauma and one in penetrating trauma) were conducted simultaneously to evaluate the efficacy and safety of recombinant factor VIIa (rFVIIa) as adjunctive therapy for control of bleeding in patients with severe blunt or penetrating trauma. METHODS Severe...

Uncontrolled bleeding is the leading cause of preventable death on the battlefield. For the recent conflicts in Iraq and Afghanistan, it has been reported that as many as 22% of such casualties could potentially survive. Protocols for substantial bleeding, typically activated after the patient’s arrival in a hospital, are known to improve trauma outcomes. Early identification of patients with s...