Accurate assessment of gestational age, fetal growth, and the detection of fetal and placental abnormalities are major benefits of sonography. Color Doppler can be used to assist in the identification of vascular architecture, detection of vascular pathology and visualization of blood flow changes associated with physiologic processes and disease states. The clinical applications of obstetrical...

Regulation of endothelial cell (EC) plasminogen activator inhibitor type-1 (PAI-1), the primary physiological inhibitor of tissue-type plasminogen activator (TPA) and urokinase-type plasminogen activator (UPA), by various stimuli has been well characterized. We report the upregulation of secreted and intracellular PAI-1 in human umbilical ECs when cocultured with human smooth muscle cells (SMCs...

background: angiogenesis, the formation of new blood vessels from preexisting ones, is one of the most important physiological and pathological processes occur in the body. in the pathological conditions such as tumor growth, psoriasis, corneal neovascularization and rheumatoid arthritis, angiogenesis is crucially required for the devolopment of the disease. zataria multiflora as a member of la...

introduction: ghrelin increases growth hormone secretion and food intake. growth hormone (gh), steroid hormones and opioids are involved in the regulation of food intake. so, they may have a role in the regulation of ghrelin secretion. we determined the effect of intravenous injections of progesterone, gh and morphine or co-administration of these hormones on ghrelin concentration and body weig...

Although umbilical venous catheterization is a routine procedure in premature newborns, it is associated with various, potentially life threatening, complications. We present a case of a premature baby diagnosed with a hepatic parenchymal liquid collection as a complication of umbilical vein catheterization in our Neonatal Intensive Care Unit. The child was born in the 25th gestational week (GW...

INTRODUCTION Although the human umbilical cord (UC) has been previously considered a medical waste, its use as a main source of fetal stem cells for regenerative medicine applications has increased over the past few years. The aim of the study was to assess the impact of the maternal age on the expression of mesenchymal stem cells (MSC) markers CD105 and CD29 in the different areas of human UC....

Danshen is a traditional Chinese medicine with many beneficial effects on cardiovascular diseases. The aim of this study was to evaluate the mechanisms responsible for the antiatherogenic effect of water soluble Danshen extracts (DEs). Rat vascular smooth muscle cells (VSMCs) and human umbilical vein endothelial cells (HUVECs) were treated with DE. To evaluate the effects of DE in vivo, carotid...

1. We have characterized the human smooth muscle endothelin converting enzyme (ECE) present in the media of the endothelium-denuded human umbilical vein preparation. 2. Endothelin-1 (ET-1) and ET-2 were potent constrictors of umbilical vein with EC50 values of 9.2 nM and 29.6 nM, respectively. ET-1 was at least 30 times more potent than ET-3 suggesting the presence of constrictor ETA receptors....

Selective deacylation of the nonhydroxylated fatty acids from S. typhimurium LPS by an acyloxyacyl hydrolase isolated from leukocytes reduces toxic activity of LPS in vivo. We examined the effect of deacylated LPS on neutrophil adherence to human umbilical vein endothelial cells (HUVE). Pretreatment of HUVE with LPS (13 ng/ml for 4 h) produced a marked increase in the adherence of subsequently ...