A lipid fraction from Escherichia coli was extracted with apolar solvents and was found to protect mice from a number of experimental bacterial infections. The benzoquinone, ubiquinone-8, was isolated from this extract by high pressure liquid chromatography and identified as such by nuclear magnetic resonance and mass spectrometry. At a dose of 25 mg/kg this substance was found to provide compl...

this study investigated the effects of coenzyme q10 (coq10) supplementation on hematological, enzymes activities and biochemical parameters in broilers with pulmonary hypertension syndrome (phs).two hundred and forty 1-d-old ross 308 male broiler chicks were randomly allocated into 3 groups with 4 replicates. from d 14, the diets were supplemented with coq10 at levels of 0, 20 and 40 mg/kg, res...

conclusions overall, coq10 was determined to have positive effects on liver injury and its related behavioral and biochemical changes. results the serum levels of alanine-aminotransferase (alt), aspartate-aminotransferase (ast), and nh4 show significant increases (p < 0.05). the groups treated with coq10 were shown to have significantly lower clinical grade of encephalopathy (p = 0.001), higher...

Some small clinical trials seem to show that coenzyme Q10 supplements can be used to lower blood pressure and to treat or prevent myalgia caused by hydroxymethylglutaryl coenzyme A reductase inhibitors (statins). However, larger trials are needed to determine if they are truly effective for these purposes. The authors examine the evidence and also discuss issues such as bioavailability, elimina...

this experiment was performed to determine the role of vitamin e and coenzyme q10 antioxidants on performance and ascites parameters of broiler chicks in cold stress conditions using a completely randomized design with 5 treatments and 5 replicates in each treatment. treatments were: positive control (pc, normal thermal conditions without antioxidants), negative control (nc, cold stress without...