A tympanic membrane perforation is more than simply a hole in the eardrum — it causes or augments hearing loss, significantly reducing patient's quality of life. The impact problems resulting from communication disorders should not be underestimated. In this paper, we introduce office-based growth factor enabled repair. Advances tissue engineering have delivered major breakthrough treatments av...

Background: It is recognized that the size of tympanic membrane(TM) perforation is proportional to the magnitude of hearing loss, however, there is no clear consensus on the effect of the location (site) of the perforation on the hearing loss. Hence the study is set to investigate the relationship between the location of perforation on TM and hearing loss. Methods: A cross-sectional prospective...