Cellular and humoral local responses were investigated following repetitive artificial Oestrus ovis infections in lambs. The presence of larvae induced a huge local recruitment of either leucocytes (T and B lymphocytes, macrophages) or granulocytes (eosinophils, mast cells and globule leucocytes). This cellular response was more pronounced in the ethmoid and sinus (development sites of second a...

We show that calmodulin-dependent phosphodiesterase (CAM-PDE) is selectively expressed in mature olfactory receptor neurons within the olfactory mucosa. Immunocytochemical staining reveals neuronal immunoreactivity that is most pronounced within cilia, dendritic knobs, and axon bundles. Neither sustentacular cells nor basal cells display immunoreactivity. The extent of loss of neuronal immunore...

A 27-year-old male presented with a 2-year history of paroxysmal sneezing and nasal congestion, which mostly occurred during April to June. Flexible fiberoptic rhinoscopy revealed slight hypertrophy of both inferior turbinates, with a normal pinkish hue and a marked cobblestone appearance of the nasopharyngeal mucosa, particularly at the torus tubarius and superior segment of the fossa of Rosen...

Understanding the properties of airflow in the nasal cavity is essential to understanding physiologic and pathologic aspects of nasal breathing. Many attempts have been made to evaluate nasal airflow patterns using the best possible analytical methods available at the time. Recently, digital particle image velocimetry (DPIV) and computational fluid dynamic methods have been applied to this area...

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy (SHML), is a systemic disease involving nodal and extranodal tissues. We report a 48-year-old female with recurrent nasal obstruction due to polypoidal masses involving the nasal sinuses, turbinates and septum bilaterally, and lumps in the right infra-orbital region and region of the right lacrimal sac. ...

Objectives: Seromucinous hamartoma, first described by Baillie and Batsakis in 1974, is a rare benign glandular proliferation of the sinonasal tract and nasopharynx. Herein, we present a case of seromucinous hamartoma arising in the bilateral nasal cavities. Case report: We present a 43-year-old woman with seromucinous hamartoma of the bilateral nasal cavities who presented with nasal obstructi...

A 6-month-old, intact, male Weimaraner dog presented to the veterinary teaching hospital for bilateral mucopurulent ocular and nasal discharge that began at approximately 10 weeks of age. A computed tomography scan showed an expansile soft-tissue mass involving both frontal sinuses, the ethmoid regions, and nasal cavities with lysis of the maxillary turbinates and hyperostosis of the walls of t...

Vertebrate fossils have been collected for hundreds of years and are stored in museum collections around the world. These remains provide a readily available resource to search for preserved proteins; however, the vast majority of palaeoproteomic studies have focused on relatively recently collected bones with a well-known handling history. Here, we characterize proteins from the nasal turbinat...

Odorant receptor (OR) genes of family mOR262 are only expressed in olfactory sensory neurons (OSNs) segregated in a central patch of the nasal turbinates; they comprise conserved DNA elements upstream of their transcription start sites that are proposed to govern the distinct expression pattern. In mouse lines with a transgene containing the coding sequence and a short upstream region of the mO...