نتایج جستجو برای: tumor necrotizing factor alpha

تعداد نتایج: 1332861  

Journal: :The Journal of pharmacology and experimental therapeutics 2009
Juan Sandoval Javier Escobar Javier Pereda Natalia Sacilotto José Luis Rodriguez Luis Sabater Luis Aparisi Luis Franco Gerardo López-Rodas Juan Sastre

Mitogen-activated protein kinases (MAPKs) are considered major signal transducers early during the development of acute pancreatitis. Pentoxifylline is a phosphodiesterase inhibitor with marked anti-inflammatory properties through blockade of extracellular signal regulated kinase (ERK) phosphorylation and tumor necrosis factor alpha production. Our aim was to elucidate the mechanism of action o...

Objective Objectives: The present study was designed to evaluate the serum lipid profile and Tumor Necrosis Factor alpha (TNF-ɑ) level in diabetic rats at the time of implantation. Type 2 diabetes mellitus (T2DM) could affect various systems, including innate immune system and causes chronic low-grade inflammation which increases the level of TNF-ɑ. Furthermore, T2DM is often accompanied by imp...

Journal: :European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005
Ram Sharony Inna Frolkis Dvir Froylich Stephan M Wildhirt Itzhak Shapira Bruno Reichart Nahum Nesher Gideon Uretzky

OBJECTIVE Pharmacologic preconditioning represents an attractive myocardial protection strategy. Tumor necrosis factor-alpha plays an important role in myocardial ischemia-reperfusion injury. We aimed to determine the effect of Monophosphoryl lipid A-induced delayed preconditioning on diastolic and systolic left ventricular function and tumor necrosis factor-alpha synthesis during ischemia and ...

Journal: :International Journal of Current Microbiology and Applied Sciences 2017

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