نتایج جستجو برای: tumor class

تعداد نتایج: 816325  

Journal: :Blood 1998
H Bosshart R F Jarrett

Hodgkin's disease is a common malignancy of the lymphoid system. Although the scarce Hodgkin and Reed-Sternberg (HRS) tumor cells in involved tissue synthesize major histocompatibility complex (MHC) class II and costimulatory molecules such as CD40 or CD86, it is unclear whether these tumor cells are operational antigen-presenting cells (APC). We developed an immunofluorescence-based assay to d...

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2018
P. S. Zeiner J. Zinke D. J. Kowalewski S. Bernatz J. Tichy M. W. Ronellenfitsch F. Thorsen A. Berger M. T. Forster A. Muller J. P. Steinbach R. Beschorner J. Wischhusen H. M. Kvasnicka K. H. Plate S. Stefanović B. Weide M. Mittelbronn P. N. Harter

Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of adaptive and innate anti-tumor response including the Human Leukocyte Antigen (HLA) machinery of antigen presentation is still unclear. We present data on the HLA class II-chaperone molecule CD74 in brain metastases and its impact on the HLA pep...

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پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی استان کرمان 1376
رضا نوروزی, پرویز غفاری,

بر اساس تجربیات انتقال دیستال اولنا یک روش خوب ترمیم بعد از اکسیزیون دیستال رادیوس بویژه در بیماران مبتلا به giant cell tumor می باشد. در این روش عود و عوارض بعد از عمل بسیار ناچیز بوده و حرکات دست در حد قابل قبولی برای بیمار حفظ می شود ولی قدرت عضلات از نوع grip دست عمل شده در حدود 75 - 50 درصد کاهش می یابد. مشکل بیمار بیشتر بعد از عمل می باشد زیرا به مدت 6 ماه باید دست داخل گچ باشد و مدت 6 ما...

15 صفحه اول
Journal: :Journal of immunology 2010
Esther M de Kruijf Anita Sajet Johanna G H van Nes Russ Natanov Hein Putter Vincent T H B M Smit Gerrit Jan Liefers Peter J van den Elsen Cornelis J H van de Velde Peter J K Kuppen

Nonclassical HLAs, HLA-E and HLA-G, are known to affect clinical outcome in various tumor types. We examined the clinical impact of HLA-E and HLA-G expression in early breast cancer patients, and related the results to tumor expression of classical HLA class I. Our study population (n = 677) consisted of all early breast cancer patients primarily treated with surgery in our center between 1985 ...

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Journal: Iranian Journal of Immunology 2012
Alireza Azargoon Farhad Shahsavar Kobra Entezami Tahereh Mousavi,

Background: Natural killer (NK) cells are the effector cells of innate immunity that respond to infection and tumor. Interactions between killer cell immunoglobulin like receptors (KIR) and human leukocyte antigen (HLA) class I molecules regulate NK cells responses to eliminate infected and transformed cells. Objective: To investigate the impact of KIR genes, HLA ligand genes, and KIR-HLA combi...

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2003
T. Cabrera G. Pedrajas J. M. Cozar A. Garrido J. Vicente M. Tallada F. Garrido Francisco Luis Diaz

Correspondence to: Dr Federico Garrido Hospital Universitario Virgen de las Nieves Department de Análisis Clı́nicos Avd. Fuerzas Armadas n 2 18014 Granada Spain Tel: þ34 958 283147] Fax: þ34 958 283147 e-mail: federico.garrido. sspa@juntadeandalucia.es Abstract: HLA class I molecules are frequently lost in a large variety of human carcinomas, possibly because of T-cell immune selection of major ...

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Journal: :Advances in cancer research 2005
Marije Marsman Ingrid Jordens Alexander Griekspoor Jacques Neefjes

Tumor vaccine development aimed at stimulating the cellular immune response focuses mainly on MHC class I molecules. This is not surprising since most tumors do not express MHC class II or CD1 molecules. Nevertheless, the most successful targets for cancer immunotherapy, leukemia and melanoma, often do express MHC class II molecules, which leaves no obvious reason to ignore MHC class II molecul...

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Journal: :Environmental Health Perspectives 1991

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Journal: :The American Journal of Pathology 2003

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Journal: :International Journal of Molecular Sciences 2019

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نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

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  • " +i+ "
    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->