background: in recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. in this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...

background: nodular hidradenoma or clear cell hidradenoma is a rare adnexal tumor arising from the eccrine glands. case report: a 60-year old female presented to the surgical out-patient clinic with complaints of breast lump of one year duration. fine needle aspirate (fna) of the lump yielded fluidly aspirate mixed with hemorrhage. on giemsa-stained smears, a possibility of benign cystic lesion...

background and objective: fine needle aspiration cytology (fnac) is well accepted as a useful diagnostic technique in the management of adult patients with head and neck lumps. but, until recently, very few reports have been obtained regarding the role of fnac in nonthyroidal neck masses in children. hence, the objective of our study was to determine the diagnostic value of fine needle aspirati...

background and objectives: involvement of lymph nodes is an important prognostic factor in the most cancers, including colorectal cancer. in the recent years, invasion to blood and lymphatic vessels has been shown to predict involvement of lymph nodes and the number of involved nodes has been less studied issue. the aim of this study was determination of the relationship between the size of col...

anaplastic thyroid carcinoma is an uncommon, highly aggressive malignancy usually presenting in the elderly. an eighteen year old boy was recently diagnosed as anaplastic carcinoma of the thyroid.  pet/cect scan performed for staging, revealed a large fdg avid heterogeneously enhancing thyroid mass with bilateral jugular venous thrombosis, which also showed increased fdg uptake, thus pointing t...

introduction uterine leiomyomas are the most common benign solid tumors of the female pelvis. retroperitoneal myomas are extremely rare and usually malignant with the common location being in the pelvis. case presentation our case involved a woman who was suffering from dysparonia and radiculating right pelvic pain. the pelvic examination revealed a palpable tender mass of about 3-4 cm in size ...

conclusions in patients with abdominal or pelvic masses and a history of previous abdominal surgery, the possibility of gossypiboma should be kept in mind. case presentation we report two patients (the first patient was 50 years old, with a history of an appendectomy three years ago in another city; the second patient was 52 years old, with a history of a cesarean section 25 years ago in anothe...

background : common variable immunodeficiency (cvid) is associated with a broad spectrum of symptoms related to infections, chronic lung diseases, autoimmune diseases, and tumors; however, solid tumors are rare complications of cvid and gastric cancer, specially, has been reported very rarely. case presentation : the present case report describes a 28 years old known case of cvid male, who was ...

introduction: acoustic transient cavitation is the primary mechanism of sonochemical reaction and has potential use for tumor treatment. in this study, the in vivo anti-tumor effect of simultaneous dual-frequency ultrasound at low-level intensity (isata < 6 w/cm2) was investigated in a spontaneous murine model of breast adenocarcinoma in balb/c mice. materials and methods: forty tumor bearing m...

the macrophages role within the tumor microenvironment has amended by a variety of factors, thus serves a vital role in tissue morphogenesis. the role of macrophages in health and disease differs enormously as the macrophage has shown dual functions. macrophage has a basic role in antigen presentation serving as the first line of defense in diseases. however the presence of cytokines and growth...