نتایج جستجو برای: tropism
تعداد نتایج: 4548 فیلتر نتایج به سال:
Rickettsiae are obligate intracellular parasitic bacteria that cause febrile exanthematous illnesses such as Rocky Mountain spotted fever, Mediterranean spotted fever, epidemic, and murine typhus, etc. Although the vector ranges of each Rickettsia species are rather restricted; i.e., ticks belonging to Arachnida and lice and fleas belonging to Insecta usually act as vectors for spotted fever gr...
Epstein-Barr virus (EBV), an oncogenic herpesvirus of humans, displays selective tropism for B lymphocytes and epithelial cells. EBV tropism is thought to be determined in part by a unique host cell receptor termed CR2 (CD21). Although previous studies have demonstrated that CR2 mediates EBV binding to B cells, its role in initiating EBV infection and B-cell transformation is less certain. In t...
Breast cancer is the most commonly diagnosed cancer in women, with approximately 182,000 women diagnosed annually in the United States-representing 26% of all cancer incidence in women. It carries the lifetime mortality risk of 3.4% in women. The defining feature of “malignancy” in breast cancer is its ability to metastasize or travel to distant sites to form secondary cancers. Breast cancer al...
Granulomatosis with polyangiitis (GPA) is a multisystemic necrotizing vasculitis special tropism to the respiratory tract and kidneys. Although uncommon, GPA may be associated hypereosinophilia limited organ involvement. In these cases, American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria insufficient establish diagnosis. We described form GPA,...
We compared the coreceptor tropism-predicting performance of a specific genotypic algorithm for HIV-1 subtype D and that of the geno2pheno algorithm with different cutoffs. The D-specific algorithm and geno2pheno with a false-positivity rate cutoff of 2.5% had the same concordance with the phenotypic determination. The geno2pheno algorithm with a false-positivity rate cutoff of 2.5%, more sensi...
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