A series of RANS-based aerodynamic shape optimization for an 800-passenger blended-wing-body aircraft is performed. A gradient-based optimization algorithm and a parallel structured multiblock RANS solver with Spalart–Allmaras turbulence model are used. The derivatives are computed using a discrete adjoint method considering both frozen-turbulence and full-turbulence assumptions. A total of 274...

The new Lcica RM 2165 automatic, heavy-duty microtome has an advanced step motor that permits an exact specimen feed and reproducible sectioning results. Features include 70 mm vertical stroke length, unique step trim function, and programmable specimen retraction. Technical features include a handwheel rocking sectioning mode; the motorized specimen feed can be linked to change the handwheel t...

The new Lcica RM 2165 automatic, heavy-duty microtome has an advanced step motor that permits an exact specimen feed and reproducible sectioning results. Features include 70 mm vertical stroke length, unique step trim function, and programmable specimen retraction. Technical features include a handwheel rocking sectioning mode; the motorized specimen feed can be linked to change the handwheel t...

The new Lcica RM 2165 automatic, heavy-duty microtome has an advanced step motor that permits an exact specimen feed and reproducible sectioning results. Features include 70 mm vertical stroke length, unique step trim function, and programmable specimen retraction. Technical features include a handwheel rocking sectioning mode; the motorized specimen feed can be linked to change the handwheel t...

Stability and control of rotors at high advance ratio are considered. Stability of teetering, articulated, and gimbaled hub types is considered with a simple flapping blade analysis. Rotor control in autorotation for teetering and articulated hub types is examined in more detail for a compound helicopter (rotor and fixed wing) using the comprehensive analysis CAMRAD II. Autorotation is found to...

Data recovery techniques for platter-based disk drives have remained rather static due to the dominance of the hard disk for the last two decades. Solid State Disk drives have differing storage and recall functionality from platter-based disks and require special care when attempting data recovery. Manufacturers have varying implementations of garbage collection in each drive, which affects the...

The new Lcica RM 2165 automatic, heavy-duty microtome has an advanced step motor that permits an exact specimen feed and reproducible sectioning results. Features include 70 mm vertical stroke length, unique step trim function, and programmable specimen retraction. Technical features include a handwheel rocking sectioning mode; the motorized specimen feed can be linked to change the handwheel t...

Introduction The question we confront is whether observations of immunologic consequences of allogeneic blood transfusion (ABT) represent only laboratory curiosities or clinically relevant alterations in the recipient’s immune function—the so-called immunomodulatory effect of ABT. The constellation of all such ABT-associated laboratory and clinical findings is known as transfusion-related immun...

TRIM RING finger proteins have been shown to play an important role in cancerogenesis, in the pathogenesis of some human hereditary disorders, and in the defense against viral infection, but the function of the majority of TRIM proteins remains unknown. Here, we show that TRIM RING finger protein TRIM2, highly expressed in the nervous system, is an UbcH5a-dependent ubiquitin ligase. We further ...

This article introduces a simulation study relating to the dynamic operating algorithm for the painted body storage (PBS) in an automotive factory. The manufacturing process in the trim shop of an automotive factory is a typical example of the mixed-model assembly production. In the paint shop, which comes before the trim shop, same-colored bodies are grouped together to reduce the changeover c...