نتایج جستجو برای: tricyclic graphs
تعداد نتایج: 101153 فیلتر نتایج به سال:
The structure of the bacterial leucine transporter from Aquifex aeolicus (LeuT(Aa)) has been used as a model for mammalian Na(+)/Cl(-)-dependent transporters, in particular the serotonin transporter (SERT). The crystal structure of LeuT(Aa) liganded to tricyclic antidepressants predicts simultaneous binding of inhibitor and substrate. This is incompatible with the mutually competitive inhibitio...
The organic anion transporting polypeptide 1A2 (OATP1A2), a membrane drug transporter expressed on important organs (such as the brain, kidney, and intestine) may be a key element in the disposition of drugs. Previous studies demonstrated that it could transport a broad spectrum of substrates, including endogenous molecules and clinically relevant drugs, such as several b-blockers and 3-hydroxy...
distance-balanced graphs are introduced as graphs in which every edge uv has the followingproperty: the number of vertices closer to u than to v is equal to the number of vertices closerto v than to u. basic properties of these graphs are obtained. in this paper, we study theconditions under which some graph operations produce a distance-balanced graph.
Abstract Palladium‐catalyzed (3+3) and (3+4) cycloannulations between vinylcyclopropanes various (hetero)aromatic aldehydes are reported. The use of phosphonate‐substituted provides access to a variety bi‐ or tricyclic heteroaromatic scaffolds via an allylation/olefination cascade. nature the mechanism was investigated by control experiments. magnified image
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