Bisamides are key fragments for the introduction of gem-diaminoalkyl residues into retroinverso pseudopeptide derivatives and in the synthesis of peptidomimetic compounds. The literature methods for these types of compounds have certain drawbacks. In particular, when amides react with electrophile-activated DMSO, the yields are rather low. We have found new electrophiles, 2,4,6-trichloro[1,3,5]...

In this work, the reaction of derivatives benzoic acid containing substituents in aromatic ring (1a-o) with 2-chloro-4,6dimethoxy-1,3,5-triazine (4) presence N-methylmorpholine (6) has been synthesized active triazine esters carboxylic acids (3a-o). These compounds obtained potassium butylate (7) vinyl acetate (2) have formed corresponding (5a-o). The electronic effect substitutor affects on ca...

THE TITLE COMPOUND [SYSTEMATIC NAME: 4,6-di-chloro-N-(2-chloro-phen-yl)-1,3,5-triazin-2-amine], C9H5Cl3N4, is a triazine fungicide. The dihedral angle between the planes of the triazine and benzene rings is 4.04 (8)°. In the crystal, two weak C-H⋯N hydrogen bonds and short Cl⋯Cl contacts [3.4222 (4) Å] link adjacent mol-ecules, forming two-dimensional networks parellel to the (112) plane. The p...

The synthesis, characterization, and host-guest chemistry of high-generation triazine dendrimers are described. With pyrene and camptothecin as guests, experiments revealed that the guest capacity of odd-generation triazine dendrimers increased until generation 7 but decreased at generation 9. Molecular dynamics simulations conducted in explicit solvent showed a useful fingerprint for this beha...

In the crystal, C(20)H(15)N(7)O(6)S, the dihedral angle between the oxadiazole and triazine rings is 86.94 (7)°. The oxadiazole ring makes a dihedral angle of 52.96 (8)° with the phenyl ring, while the triazine ring makes a dihedral angle of 82.08 (7)° with the benzene ring. In the structure, mol-ecules are linked by a pair of N-H⋯O hydrogen bonds, forming an inversion dimer. The dimers are fur...

A procedure for immobilization of well-defined quantities of oligodeoxyribonucleotides (ODNs) to a versatile nylon support is described. The solid support, a nylon-6/6 bead, is covalently coated with poly(ethyleneimine) to provide a reactive spacer-arm for attachment of ODNs. 5'-Aminohexyl-tailed ODNs are selectively activated using 2,4,6-trichloro-1,3,5-triazine (cyanuric chloride) and then co...

The NCNN group is an essential part of various heterocycles bearing high biological activities. 1,2,4-Triazines and their condensed derivatives found applications as pharmaceuticals and in agriculture. For example vardenafil ñ phosphodiesterase inhibitor, is useful in the treatment of male erectile dysfunctions (1), apazone exhibit anti-inflammatory and analgesic actions (2), lamotrigine is use...

The synthesis of tailormade thin-film composite (TFC) nanofiltration (NF) membranes produced by interfacial polymerization is presented for the separation unspent (MEA-triazine) and spent (DTZ) H2S scavengers obtained from an oil gas wastewater offshore installation in North Sea. physicochemical properties, thermal stability, hydrophilicity synthesized TFC were investigated using SEM, FTIR, XRD...

In the title compound, C(7)H(9)N(5)O(2)S, the pyrazolo-[4,3-e][1,2,4]triazine fused-ring system is essentially planar [maximum deviation = 0.0420 (3) Å]. In the crystal, mol-ecules related by twofold axes are linked into a mol-ecular net via inter-molecular C-H⋯O and C-H⋯N hydrogen bonds. π-π inter-actions are observed between the triazine and pyrazole rings of mol-ecules related by the the two...

Eleven compounds have been synthesized in a series of [1, 3, 5] triazine analogues which, in addition to 4-amino benzonitrile, contain 8-hydroxy quinoline and different piperazines as well as piperidine substituents on the C-6 position of s-triazine ring. The title compounds were then evaluated for their in vitro microbial activity against 2 gram –Ve bacteria (E.coli, P. aeruginosa), 2 gram +Ve...