Some new isomeric structures of pyrimido[2,1-c][1,2,4]triazines 4-8 and 10-14 have been synthesized via the ring closure reactions of 2-hydrazinyl-1-methylpyrimidine 3 and/or 2-hydrazinopyrimidine 9 with acyclic and cyclic oxygen compounds under various conditions. Structures of the targets have been established from their elemental analyses and spectral data (UV, IR, 1H/13C NMR and mass spectr...