Gruentzig A: Transluminal dilatation of coronary artery stenosis. Lancet 1: 263, 1978 Kent KM, Bentiusglio LG, Block PC, et al: Percutaneous transluminal coronary angioplasty: report from the NHLBI registry. Am J Cardiol 49: 2011-2020, 1982 Doros G, Cowley MI, Simpson J, et al: Percutaneous transluminal coronary angioplasty report of complications from the National Heart Lung and Blood Institut...

The myelin P0 protein is glycosylated at a single site, asparagine 93, within its only immunoglobulin (Ig)-like domain. We have previously shown that P0 behaves like a homophilic adhesion molecule (Filbin, M. T., F. S. Walsh, B. D. Trapp, J. A. Pizzey, and G. I. Tennekoon. 1990. Nature (Lond.). 344:871-872). To determine if the sugar residues of this molecule contribute to its adhesiveness, the...

The tensile behavior of single phase tantalum-hydrogen alloys and tantalum-molybdenum alloys containing dilute additions of molybdenum has been studied as a function of grain size and alloying addition. Uniaxial tension tests were carried out at 25C and -196C, the strain rate.£ , being fixed throughout the experiments at 10-3 sec-l. The parameters (fi and ky of the Fetch equation were evaluated...

discrete staining of cell bodies was found with type I sera in the newborn or 5-day-old rats. In the newborn there was a diffuse staining of the parenchyma of the developing cortex and other areas. Type I1 staining was observed, particularly in those cells with developed perikarya. By 9 days type I sera began to show, although only weakly, some cells in the cortex and hippocampus. At 14 days so...

The extracellular domain of the myelin P0 protein is believed to engage in adhesive interactions and thus hold the myelin membrane compact. We have previously shown that P0 can behave as a homophilic adhesion molecule through interactions of its extracellular domains (Filbin, M. T., F. S. Walsh, B. D. Trapp, J. A. Pizzey, and G. I. Tennekoon. 1990. Nature (Lond.) 344:871-872). To determine if t...

Current research into regeneration of the nervous system has focused on defining the molecular events that occur during regeneration. One well-characterized system for studying nerve regeneration is the sciatic nerve of rat. Numerous studies have characterized the sequence of events that occur after a crush injury to the sciatic nerve (Cajal 1928; Hall 1989). These events include axon and myeli...

Barnett and Prineas recently reported new morphological findings in the brain of a 14-year-old patient with relapsing-remitting multiple sclerosis (MS) who died within 24 hours of the onset of a new symptomatic and fatal brainstem lesion. Within this early lesion, they observed extensive oligodendrocyte cell death which they attributed to apoptosis. Strikingly, no T lymphocytes were detected in...

WITHIN HIGHER EDUCATION, effective delivery of psychology teaching and learning is facing a number of challenges. Recent social and financial changes (e.g. widening participation, higher tuition fees, reduced resource funding) has resulted in larger, more diverse cohorts of students with increasing expectations for high quality teaching and support, delivered through a ‘value-for-money’ curricu...

Apicomplexa are obligate intracellular parasites that cause tremendous disease burden world-wide. They utilize a set of specialized secretory organelles in their invasive process that require delivery of components for their biogenesis and function, yet the precise mechanisms underpinning such processes remain unclear. One set of potentially important components is the multi-subunit tethering c...

Current research into regeneration of the nervous system has focused on defining the molecular events that occur during regeneration. One well-characterized system for studying nerve regeneration is the sciatic nerve of rat. Numerous studies have characterized the sequence of events that occur after a crush injury to the sciatic nerve (Cajal 1928; Hall 1989). These events include axon and myeli...