The interaction of proteins with DNA results, in some cases, in DNA bending, and this might have functional importance. However, when the protein-induced bending of DNA is small, its measurement presents a problem. It is shown that the fluorescence resonance energy transfer between fluorophores placed on the ends of the specially designed U-shaped DNA, which contains the DNA-binding sites at it...

The design strategies for band-pass modulators are discussed. This paper studies two different approaches: the use of resonators and the synthesis of the noise transfer function (NTF) starting from a closer function. The use of a MASH configuration to obtain multiple zeros or splitting the complex zeros of the NTF is also discussed. The sensitivity to components mismatch of the proposed solutio...

Current data suggests that the transferring of immunologically specific information by transfer factor molecules requires interaction with a cell that has been genetically programmed to be antigen reactive but at the time of interaction is unprimed. Contact with transfer factor molecules would allow a naive recipient, on a first encounter with antigen, to make a secondary rather than a primary ...

The availability of protein fluorophores with appropriate spectral properties has made it possible to employ fluorescence resonance energy transfer (FRET) to assess interactions between three proteins microscopically. Flow cytometry offers excellent sensitivity, effective signal separation and the capacity to assess a large number of events, and, therefore, should be an ideal means to explore p...

The Langlands-Shelstad transfer factor is a function defined on some reductive groups over a p-adic field. Near the origin of the group, it may be viewed as a function on the Lie algebra. For classical groups, its values have the form q sign, where sign ∈ {−1, 0, 1}, q is the cardinality of the residue field, and c is a rational number. The sign function partitions the Lie algebra into three su...

The naturally occurring transmissible plasmid pAV1 mediates chromosome transfer and can exhibit two distinct levels of transmissibility in Acinetobacter calcoaceticus strain EBF65/65. The two states of pAV1 have been arbitrarily designated pAV1a (low frequency variant) and pAV1b (high frequency variant). Both variants have the same incompatibility and host range properties and each mobilizes tw...

This paper describes a technique for synthesizing any noise shaping transfer function (NTF) starting from an N-Path Sigma Delta architecture. The proposed method uses cross-coupled paths to obtain missing terms in the NTF. The limitations due to zeros located out of the band of interest, as it happens for conventional N-Path Σ∆ modulators, are avoided. Specific NTFs are synthesized and behaviou...