نتایج جستجو برای: transcript level

تعداد نتایج: 1105617  

2018
Neda Rezvan Ashraf Moini Sattar Gorgani-Firuzjaee Mohammad Javad Hosseinzadeh-Attar

OBJECTIVES Polycystic ovary syndrome (PCOS), an ovarian-pituitary axis androgen disorder, is a common endocrine disease in women. Obesity-induced androgenesis and imbalance of adipokine secretion may lead to some metabolic features of PCOS. The beneficial effects of polyphenolic compounds such as quercetin have been reported, however, the underlying molecular mechanism is not entirely understoo...

Journal: :Blood 2004
Gianantonio Rosti Giovanni Martinelli Simona Bassi Marilina Amabile Elena Trabacchi Barbara Giannini Daniela Cilloni Barbara Izzo Antonio De Vivo Nicoletta Testoni Giovanna Rege Cambrin Francesca Bonifazi Simona Soverini Simona Luatti Enrico Gottardi Daniele Alberti Fabrizio Pane Francesco Salvatore Giuseppe Saglio Michele Baccarani

Imatinib is a tyrosine-kinase inhibitor that binds to ABL proteins and induces cytogenetic remissions in patients with chronic myeloid leukemia (CML). In these patients measuring response by molecular techniques is clearly required. We determined the cytogenetic and molecular response (CgR, MR) to imatinib in 191 patients with late chronic-phase Philadelphia-positive (Ph+) CML, previously treat...

2010
Shuhua Liu Chengwei Zhang Baojun Yang Jianhua Gu Zewen Liu

Juvenile hormone (JH) plays key roles in both metamorphosis and adult reproductive processes. Farnesoic acid O-methyltransferase (FAMeT) is thought to be an important enzyme in the JH biosynthetic pathway, catalyzing methylation of farnesoic acid (FA) to methyl farnesoate (MF). A full-length cDNA (NlFAMeT) encoding a 299 amino acid putative FAMeT was isolated from the brown planthopper, Nilapar...

2010
Seol Ah Noh Haeng-Soon Lee Eun Joo Huh Gyung Hye Huh Kyung-Hee Paek Jeong Sheop Shin Jung Myung Bae

A sweetpotato (Ipomoea batatas cv. 'Jinhongmi') MADS-box protein cDNA (SRD1) has been isolated from an early stage storage root cDNA library. The role of the SRD1 gene in the formation of the storage root in sweetpotato was investigated by an expression pattern analysis and characterization of SRD1-overexpressing (ox) transgenic sweetpotato plants. Transcripts of SRD1 were detected only in root...

Journal: :Genetics and molecular research : GMR 2014
L-L Guan W Wu B Hu D Li J-W Chen K Hou L Wang

Three ω-3 fatty acid desaturase genes (CtFAD3, CtFAD7, and CtFAD8) were isolated from safflower (Carthamus tinctorius L.). Transcript analysis showed that the highest transcript levels were detected for CtFAD3 and the low transcript levels were detected for CtFAD7 and CtFAD8 in flowers. This result indicates that CtFAD3 enzyme activity is important for fatty acid desaturation in flowers. The lo...

2011
Alexander T. Fleck Thandar Nye Cornelia Repenning Frank Stahl Marc Zahn Manfred K. Schenk

The beneficial element silicon (Si) may affect radial oxygen loss (ROL) of rice roots depending on suberization of the exodermis and lignification of sclerenchyma. Thus, the effect of Si nutrition on the oxidation power of rice roots, suberization and lignification was examined. In addition, Si-induced alterations of the transcript levels of 265 genes related to suberin and lignin synthesis wer...

Journal: :Journal of bacteriology 2011
Marcha L Gatewood Patricia Bralley George H Jones

We have examined the expression of the rpsO-pnp operon in an RNase III (rnc) mutant of Streptomyces coelicolor. Western blotting demonstrated that polynucleotide phosphorylase (PNPase) levels increased in the rnc mutant, JSE1880, compared with the parental strain, M145, and this observation was confirmed by polymerization assays. It was observed that rpsO-pnp mRNA levels increased in the rnc mu...

Journal: :Journal of bacteriology 2013
Yi Wen Jing Feng George Sachs

Urease is an essential component of gastric acid acclimation by Helicobacter pylori. The increased level of urease in gastric acidity is due, in part, to acid activation of the two-component system consisting of the membrane sensor HP0165 (ArsS) and its response regulator HP0166 (ArsR), which regulates transcription of the seven genes in two separate operons (ureAB and ureIEFGH) of the urease g...

2008
Jan C. Schöning Corinna Streitner Irmtraud M. Meyer Yahong Gao Dorothee Staiger

The Arabidopsis RNA-binding protein AtGRP8 undergoes negative autoregulation at the post-transcriptional level. An elevated AtGRP8 protein level promotes the use of a cryptic 5' splice site to generate an alternatively spliced transcript, as_AtGRP8, retaining the 5' half of the intron with a premature termination codon. In mutants defective in nonsense-mediated decay (NMD) abundance of as_AtGRP...

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