نتایج جستجو برای: trachoma
تعداد نتایج: 1846 فیلتر نتایج به سال:
Trachoma is the commonest infectious cause of blindness worldwide. Recurrent infection of the ocular surface by Chlamydia trachomatis, the causative agent, leads to inturning of the eyelashes (trichiasis) and blinding corneal opacification. Trachoma is endemic in more than 50 countries. It is currently estimated that there are about 1.3 million people blind from the disease and a further 8.2 mi...
Ocular infection with Chlamydia trachomatis can lead to trachoma, a leading infectious cause of blindness. Trachoma is targeted for elimination by 2020. Clinical grading for ocular disease is currently used for evaluating trachoma elimination programs, but serological surveillance can be a sensitive measure of disease transmission and provide a more objective testing strategy than clinical grad...
Trachoma, the world’s leading infectious cause of blindness, affects over 300 million people globally. Caused by the bacterium Chlamydia trachomatis, the disease thrives in environments with poor access to water, sanitation, and hygiene. It is spread from one person to another by eye-seeking flies, and by sharing cloths used to wipe the eyes and hands. Repeated or persistent infection can lead ...
The immediate study objective was to determine if variable disease severity in children with trachoma could be attributable in part to host variation in the ability to clear Chlamydia trachomatis infection. Identification of sibling cohorts with these variant phenotypes would be useful for immunogenetic studies. A weekly survey for 3 months in a trachoma-hyperendemic village using detection of ...
OBJECTIVE The study compares the effectiveness of two strategies for distributing azithromycin in an area with mild-to-moderate active trachoma in Nepal. METHODS The two strategies investigated were the use of azithromycin for 1) mass treatment of all children, or 2) targeted treatment of only those children who were found to be clinically active, as well as all members of their household. ...
caused by the bacterium Chlamydia tracho-matis. Bacteria can spread via an infected person's hands or clothing and may be carried by flies that have come into contact with discharge from the eyes or nose of an infected person. Infants and children below school age are more likely to be infected. Since trachoma is transmitted through close personal contact, it often infects children in entire co...
Eastern Africa, which comprises Eritrea, Ethiopia, Kenya, South Sudan, Sudan, Tanzania and Uganda, has the highest burden of trachoma in the world. In sub-Saharan Africa, there are 1,274 districts known to be endemic for trachoma (i.e., the incidence of trachomatous inflammation – follicular (TF) is > 5%). Of these, 769 are found within the seven Eastern African countries, which represents over...
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