Introduction: Idiopathic subglottic tracheal stenosis is a rare inflammatory disease of the trachea; most commonly affects females within the age range of 20-50 years. No etiologic factor has yet been identified for this rare tracheal disease and therefore it should be diagnosed after the exclusion of other inflammatory, traumatic, and autoimmune diseases of the trachea. The familial or g...

background: pancreatic anastomosis leakage and fistula formation following  pancreaticoduodenectomy (whipple’s procedure) is a common complication. delay in timely diagnosis and proper management is associated with high morbidity and mortality. to report our experience with management of pancreatic fistula following whipple’s procedure. materials and methods: in this retrospective study, medica...

we report a case of a woman presenting in a state of shock with classic symptoms of ruptured ectopic pregnancy. she had a history of tubal ligation done three years back. exploratory laparotomy was done, and a diagnosis of ruptured ectopic ovarian pregnancy was made.

OBJECTIVE Long-segment tracheal stenosis is rare, life-threatening, difficult, and expensive to treat. Management remains controversial. A multidisciplinary tracheal team was formed in 2000 to deal with a large number of children with airway problems referred for management. We review the effect of that service, comparing the era before and after the establishment of the multidisciplinary trach...

OBJECTIVE To characterize tracheal intubation process of care and safety outcomes in a large tertiary pediatric intensive care unit using a pediatric adaptation of the National Emergency Airway Registry. Variances in process of care and safety outcome of intubation in the pediatric intensive care unit have not been described. We hypothesize that tracheal intubation is a common but high-risk pro...

BACKGROUND To determine the sensitivity and specificity of the self-inflating bulb (SIB) to verify tracheal intubation in out-of-hospital cardiac arrest patients. METHODS Sixty-five consecutive adult patients with out-of-hospital cardiac arrest were enrolled. Patients were provided chest compression and ventilation by either ba-valve-mask or the esophageal tracheal double-lumen airway by ambu...

Die Sortase-vermittelte Ligation (Engl. sortase-mediated ligation, SML) ist ein effektives Werkzeug der Proteinchemie, welches die von Peptiden mit LPxTG-Sortiermotiven und N-terminalen Glycin-Nukleophilen ermöglicht. Kopplung mehrerer Fragmente durch SML wird den erneuten Einbau eines Sortiermotivs in das Produkt verhindert. Hier beschreiben wir Multi-Fragment-SML auf Grundlage schaltbaren Sor...

Oxygen delivery in many animals is enabled by the formation of unicellular capillary tubes that penetrate target tissues to facilitate gas exchange. We show that the tortuous outgrowth of tracheal unicellular branches towards their target tissues is controlled by complex local interactions with target cells. Slit, a phylogenetically conserved axonal guidance signal, is expressed in several trac...