نتایج جستجو برای: toxigenic activity
تعداد نتایج: 1137657 فیلتر نتایج به سال:
Aspects of the biology of T. pallidum subsp. pallidum, the agent of syphilis, are examined in the context of a century of experimental studies and the recently determined genome sequence. T. pallidum and a group of closely related pathogenic spirochetes have evolved to become highly invasive, persistent pathogens with little toxigenic activity and an inability to survive outside the mammalian h...
A polyether antibiotic, ecteinamycin (1), was isolated from a marine Actinomadura sp., cultivated from the ascidian Ecteinascidia turbinata. 13C enrichment, high resolution NMR spectroscopy, and molecular modeling enabled elucidation of the structure of 1, which was validated on the basis of comparisons with its recently reported crystal structure. Importantly, ecteinamycin demonstrated potent ...
Bacillus anthracis is a powerful agent for use in biological warfare, and infection with the organism is associated with a high rate of mortality, underscoring the need for additional effective therapies for anthrax. Radioimmunotherapy (RIT) takes advantage of the specificity and affinity of the antigen-antibody interaction to deliver a microbicidal radioactive nuclide to a site of infection. R...
Pollen is used in the human diet as a food supplement because of its high nutritional value; however, this product is prone to fungal contamination that could potentially generate toxins that are harmful to human health. This study aimed to verify the floral diversity of commercial brands of bee pollen and their mycotoxicological safety for human consumption. A total of 27 bee pollen samples we...
Most harmful diatoms belong to the marine, planktonic genus Pseudo-nitzschia and are responsible for amnesic shellfish poisoning through the production of domoic acid. Fifteen Pseudo-nitzschia species, nine of them toxigenic (approximately 60% of the species found in our samples) were recovered from 185 ship ballast tanks (water and sediment) destined for Canadian ports. Our results demonstrate...
BACKGROUND The aim of this study was to develop and validate a multiplex real-time PCR assay for simultaneous identification and toxigenic type characterization of Clostridium difficile. METHODS The multiplex real-time PCR assay targeted and simultaneously detected triose phosphate isomerase (tpi) and binary toxin (cdtA) genes, and toxin A (tcdA) and B (tcdB) genes in the first and sec tubes,...
the aim of this study was to determine the occurrence of enterotoxigenic and enteroaggregative escherichia coli strains and antibiotic resistance of the isolates in raw milk and unpasteurized cheese. out of 200 samples of raw milk and 50 samples of unpasteurized cheeses, 96 and 24 strains of e. coli were isolated, respectively. polymerase chain reaction (pcr) was used to detect the genes encodi...
clostridium difficile is a frequently identified cause of nosocomial gastrointestinal disease. it has been proved to be a causative agent in antibiotic-associated diarrhea, antibiotic-associated colitis, and pseudomembraneous colitis. this study was aimed to determine the prevalence of c.difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. the 942 hospitalized patie...
Contamination of maize and barley grain during storage by the toxigenic fungi Aspergillus flavus (A. flavus) Penicillium Verrucosum (P. verrucosum) is both an economic a public health problem, especially in less industrialized countries. Peracetic acid (PA) compound used for disinfection food contact surfaces. Unlike other disinfectants, it leaves no toxic residues its decomposition products (C...
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