Species differences in the metabolism of xenobiotics can present significant problems for safety and efficacy assessment during the development of new pharmaceutical agents. Identification of animal models for human metabolism and/or toxicology of any particular compound would significantly reduce the extent and cost of animal testing of novel candidate pharmaceuticals. Sulfation is an importan...

Bacterial multicomponent monooxygenases (BMMs) are members of a wide family of diiron enzymes that use molecular oxygen to hydroxylate a variety of aromatic compounds. The presence of genes encoding for accessory proteins not involved in catalysis and whose role is still elusive, is a common feature of the gene clusters of several BMMs, including phenol hydroxylases and several soluble methane ...

Abstract This study demonstrated the interaction mechanism of collagen peptides (CPs) with 4-ethylphenol (4-EP), phenol, guaiacol, and 4-ethylguaiacol (4-EG) in ethanol-water solution. The ultraviolet visible spectroscopy, zeta potential tests hydrogen nuclear magnetic spectroscopy manifested that CPs interacted phenolic compounds. Meanwhile, Isothermal titration calorimetry determination indic...

Hydrogels are widely studied for chemical sensors. However, they are known to adsorb organic compound and metal ions. The adsorption abilities of hydrogels against organic compounds and metal ions will negatively affect the performance of a hydrogel based chemical sensor. To clarify the effect of hydrophobic pollution on swelling behavior of temperature-sensitive gel, the temperature-responses ...

Nutmeg (Myristica fragrans Houtt.) is native to Indonesia. One of the nutmeg products that are traded and exported seeds. or what commonly called in great demand because it contains many aromatic compounds form essential oils. This study aims extract determine composition seed oils based on differences coat color. Fresh samples were extracted analyzed using GC-MS. The results showed twelve iden...

In oder to discover potentially active antibacterial compounds, three Schiff bases: 2[(4-methoxybenzylidene)-amino]phenol (5), 2-[(3,4-dimethoxybenzylidene)-amino]phenol (6), 2-[(3,4,5-trimethoxybenzylidene)-amino]phenol (7), were synthesized by the condensation of 2-aminophenol (1) with aldehydes (2-4) in methanol along with H2SO4. The synthesized Schiff bases (5-7) were characterized by H-NMR...