Chronic hepatitis B infection (CHB) is characterized by sub-optimal T cell responses to viral antigens. A therapeutic vaccine capable of restoring these immune responses could potentially improve HBsAg seroconversion rates in the setting of direct acting antiviral therapies. A yeast-based immunotherapy (Tarmogen) platform was used to make a vaccine candidate expressing hepatitis B virus (HBV) X...

A green and easy technique was used to synthesize silver silica (Ag@SiO2) core–shell nanoparticles (NPs) in the matrix blend polymers matrix. Core–shell were loaded into polyvinyl alcohol (PVA) ultrahigh molecular weight polyethylene oxide (UHMW-PEO) blended polymer fabricate new nanocomposite films (NCFs) using developed solution-sonication-casting technique. The spectroscopic properties of re...

BACKGROUND The measurement of hepatitis C virus core antigen (HCV-coreAg) has been shown to be an indicator of active HCV infection. The aim of the present study was 1) to investigate the stability and effectiveness of HCV-coreAg and HCV-RNA quantification in HCV infection with or without HIV-1 coinfection, 2) to explore the association between the HCV-coreAg/HCV-RNA (Ag/RNA) ratio and the immu...

The title compound, [Ag(C(72)H(84)N(4)O(4))], crystallizes with the Ag(II) cation on a centre of symmetry. The macrocyclic 24-membered ring core is planar with a mean deviation of 0.0311 (15) Å and the four-coordinate Ag(II) cation fits into its center, at 2.0814 (19) and 2.0872 (19) Å, from the surrounding pyrrole-N atoms, in agreement with what is found in related compounds. The p-heptyl-oxyp...

The Zone 5 Cu-Ag deposit is the most consistently (for ～4.2 km) mineralized in Khoemacau district northwestern Botswana, with an underground mineable resource of ～100 Mt grading 2 % Cu and 21 g/t Ag. consists a redox-buffered metal-zoned ore body hosted preferentially by chemically reduced meta-sediments overlying oxidized hematite-bearing arkosic sandstone. Ore-grade mineralization typically v...

Silver (Ag) nanoparticles were produced using DNA extracted from salmon milt as templates. Particles spherical in shape with an average diameter smaller than 10 nm were obtained. The nanoparticles consisted of Ag as the core with an outermost thin layer of DNA. The DNA/Ag hybrid nanoparticles were immobilized over the surface of cotton based fabrics and their antibacterial efficiency was evalua...

A fast, generic, and suspension-based route to highly SERS-active assemblies of noble metal nanoparticles (Au, Ag) with small core-satellite gaps and single-particle Raman sensitivity is presented. Rationally designed, heterobifunctional Raman reporters serve as molecular linkers for electrostatic conjugation of the small satellites to the large core.