METHOD(S) : In this prospective cohort study conducted over a 8 months period (January to August 2005) 416 antenatal women admitted with threatened preterm labor and in preterm labor, with or without rupture of membranes, were recruited. They were followed up from admission till delivery and discharge. Gestational age at onset of preterm labor, associated risk factors, response to tocolytics if...

OBJECTIVE To assess the outcome of external cephalic version for routine management of malpresenting foetuses at term. DESIGN Prospective observational study. SETTING Tertiary teaching hospital, Malaysia. PATIENTS From September 2003 to June 2004, a study involving 41 pregnant women with malpresentation at term was undertaken. An external cephalic version protocol was implemented. Data we...

One of the most established roles of oxytocin (OT) is in inducing uterine contractions and labor. Apart from inducing contractions, our recent studies showed that OT can also activate proinflammatory pathways in both human myometrial and amnion cells, which suggests that the proinflammatory role of OT should be taken into account when developing tocolytics targeting the OT/oxytocin receptor (OT...

The adrenergic system plays a major role in the regulation of the contractility of the uterus during pregnancy. This study investigated the role of the alpha(1A)-adrenergic receptor (AR) in this regulation. The use of partial phosphorothioate antisense oligodeoxynucleotides (AONs) permitted the sequence-selective inhibition of AR gene expression. AONs were injected together with a cationic lipo...

OBJECTIVE To determine the success rate of External Cephalic Version (ECV) with 0.25 mg Salbutamol in singleton term breech and to identify the predictors of success. STUDY DESIGN Quasi experimental study. PLACE AND DURATION OF STUDY Mother and Child Health Centre, Pakistan Institute of Medical Sciences, Islamabad, from January 2000 to March 2005. METHODOLOGY Women, presenting with uncomp...

conclusions this study showed that some properties of antimicrobial substances produced by the ga strain differed from other peptide antibiotics produced by the genus bacillus such as bacitracin, which increases the likelihood of its novelty. results the isolated bacterium was identified as a new strain of bacillus atrophaeus. the antimicrobial substance exhibited heat stability between 25ºc an...

OBJECTIVES The aim of this study was to determine if the actions of progesterone on preterm labor are accomplished through modulation of the percentage of regulatory T-cells (Treg). METHODS The study was a cohort pilot study made in a single center tertiary obstetrical unit with women in preterm labor arrested with tocolytic treatment. Variation of the number and percentage of Treg cells obta...