The addition of aryl groups to unactivated olefins represents a direct approach to C!C bond construction. Pd-catalyzed coupling of aryl halides with alkenes, the Heck reaction, offers a viable approach to arylation. However, terminal unactivated olefins often display low reactivity in Heck reactions and can yield mixtures of styrenes and allyl arenes owing to poor regiocontrol in the b-hydride ...

We have studied the formation and carried out an in vivo evaluation of carbonate apatite (CO3-Ap) and CO3-Ap/CaCO3 composite coatings on titanium substrates using the thermal substrate method. The coatings were formed on commercial pure titanium rods (diameter = 2mm, length = 5mm) and plates (thickness = 0.3mm) by the thermal substrate method in an aqueous solution that contained Ca(H2PO4)2, Ca...

The effects of calcium (Ca) or strontium (Sr) on host osteogenesis and immune responses have been investigated separately. In clinical practice, these two elements may both be present around an orthopedic device, but their potential synergistic effects on osteogenesis and the immune response have not been explored to date. In this work, we investigated the immunomodulatory effects of Ca and Sr ...

Ti implants are highly biocompatible and allow orderly bone growth but, unfortunately, in the first five years after implantation, 5–10% of them fail due to poor osseointegration presence bacterial infections prosthesis. Silver nanoparticles have been described damage cell via prolonged release Ag+ ions as a mode action when immobilized on surface. In this work, two routes synthetize silver pro...

Surface modification of titanium (Ti) implants are extensively studied in order to obtain prominent biocompatibility and antimicrobial activity, especially preventing implant-associated infection. In this study, Ti substrates surface were modified by graphene oxide (GO) thin film and silver (Ag) nanoparticles via electroplating and ultraviolet reduction methods so as to achieve this purpose. Mi...

The research here described presents an investigation over the efficiency of nanostructured TiO2 films as photocatalysts either in air purification systems or to be integrated in light devices, based on the exploitation of UV or Vis irradiation to induce the degradation of hazardous chemical compounds. Gas pollutants (NO) and dyes (rhodamine B) will be considered as model reactants. Several oxi...

The ability to create patterns of bioactive nanomaterials particularly on metallic and other types of implant surfaces is a crucial feature in influencing cell response, adhesion and growth. In this report, we uncover and elucidate a novel method that allows the easy deposition of a wide variety of predetermined topographical geometries of nanoparticles of a bioactive material on both metallic ...