نتایج جستجو برای: tissue tropism

تعداد نتایج: 921469  

2017
Myriam Lawand Julie Déchanet-Merville Marie-Caroline Dieu-Nosjean

The unique features of gamma-delta (γδ) T cells, related to their antigen recognition capacity, their tissue tropism, and their cytotoxic function, make these cells ideal candidates that could be targeted to induce durable immunity in the context of different pathologies. In this review, we focus on the main characteristics of human γδ T-cell subsets in diseases and the key mechanisms that coul...

2013
Martyn K. White Jennifer Gordon Kamel Khalili

Since their discovery in 1971, the polyomaviruses JC (JCPyV) and BK (BKPyV), isolated from patients with progressive multifocal leukoencephalopathy and polyomavirus-associated nephropathy, respectively, remained for decades as the only known members of the Polyomaviridae family of viruses of human origin. Over the past five years, the application of new genomic amplification technologies has fa...

Journal: :Journal of virology 2005
Maria Kontou Lakshmanan Govindasamy Hyun-Joo Nam Nathan Bryant Antonio L Llamas-Saiz Concepción Foces-Foces Eva Hernando Mari-Paz Rubio Robert McKenna José M Almendral Mavis Agbandje-McKenna

Two strains of the parvovirus minute virus of mice (MVM), the immunosuppressive (MVMi) and the prototype (MVMp) strains, display disparate in vitro tropism and in vivo pathogenicity. We report the crystal structures of MVMp virus-like particles (MVMp(b)) and native wild-type (wt) empty capsids (MVMp(e)), determined and refined to 3.25 and 3.75 A resolution, respectively, and their comparison to...

Journal: :Diseases of aquatic organisms 2007
K Molnár S Marton E Eszterbauer C Székely

Myxobolus gayerae sp. n. and M. leuciscini González-Lanza & Alvarez-Pellitero, 1985 (Myxozoa: Myxobolidae) have been described and re-described from European chub Leuciscus cephalus L. from the Hungarian stretch of the river Danube. The ellipsoidal plasmodia of M. gayerae sp. n. were found in the mucosa of the intestinal wall, whereas the large, elongated plasmodia of M. leuciscini infected the...

Journal: :The Journal of antimicrobial chemotherapy 2013
Soham Gupta Ujjwal Neogi Hiresave Srinivasa Anita Shet

OBJECTIVES Genotypic tropism testing (GTT) of HIV is increasingly used prior to the initiation of CCR5 antagonist therapy in HIV-infected individuals. Normally performed on plasma-derived virus, the test is challenging when performed in patients with suppressed viraemia. We aimed to evaluate the performance of cell-associated proviral DNA against plasma-derived viral RNA as the genetic material...

2017
Dinesh Mohan Chaudhari Pushpendra Nath Renjen Raman Sardana Hena Butta

By definition, a brain abscess is an intraparenchymal collection of pus. Nocardia shows to have a special tropism for the neural tissue. Solitary abscess represents the most common manifestation in the central nervous system, accounting for 1%-2% of all cerebral abscesses. In this report, we present a case of primary multiple brain abscesses due to Nocardia farcinica in an immune competent pati...

Journal: :Memorias do Instituto Oswaldo Cruz 2010
Luciana O Andrade Lúcia M C Galvão Maria de Nazareth S L Meirelles Egler Chiari Sergio D J Pena Andrea M Macedo

We have previously demonstrated selection favoring the JG strain of Trypanosoma cruzi in hearts of BALB/c mice that were chronically infected with an equal mixture of the monoclonal JG strain and a clone of the Colombian strain, Col1.7G2. To evaluate whether cell invasion efficiency drives this selection, we infected primary cultures of BALB/c cardiomyocytes using these same T. cruzi population...

Journal: :Journal of the Medical Association of Thailand = Chotmaihet thangphaet 2007
Sombat Kunakornsawat Kitipod Ngamlamaidt Rachata Tungsiripat Thavat Prasartritha

SUMMARY OF BACKGROUND DATA The association between the facet tropism and the development of lumbar disc herniation has been studied; however the results remain controversial. OBJECTIVE To determine the association between the facet tropism and the development of lumbar disc herniation. STUDY DESIGN A cross-sectional study. MATERIAL AND METHOD MRI of 34 patients with lumbar disc herniation...

Journal: :Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2015
Alejandro Pironti Saleta Sierra Rolf Kaiser Thomas Lengauer Nico Pfeifer

BACKGROUND geno2pheno[coreceptor] is a bioinformatic method for genotypic tropism determination (GTD) which has been extensively validated. OBJECTIVES GTD can be affected by sequencing/base-calling variability and unreliable representation of minority populations in Sanger bulk sequencing. This study aims at quantifying the robustness of geno2pheno[coreceptor] with respect to these issues. GT...

2017
Giorgia Beffagna Cinzia Centelleghe Giovanni Franzo Giovanni Di Guardo Sandro Mazzariol

Dolphin morbillivirus (DMV) has been deemed as one of the most relevant threats for fin whales (Balaenoptera physalus) being responsible for a mortality outbreak in the Mediterranean Sea in the last years. Knowledge of the complete viral genome is essential to understand any structural changes that could modify virus pathogenesis and viral tissue tropism. We report the complete DMV sequence of ...

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