introduction: a desirable characteristic of root canal irrigants is the ability of dissolving soft tissues. sodium hypochlorite, an antibacterial and tissue solvent irrigant used in endodontic treatment is known to be toxic for periapical tissues. chlorhexidine gluconate, an effective antimicrobial agent, is another irrigant with limited tissue dissolving ability. a mixture of a tetracycline is...

conversion of knee arthrodesis to total knee arthroplasty is a difficult procedure accompanied by many complications due to soft tissue and extensor mechanism contracture and bone defects. we report two cases of distal femur osteosarcoma that had been undergone wide resection arthrodesis initially. arthrodesis was converted to total knee arthroplasty with hinged prosthesis after many years. we ...

In 21 patients ultrasound-guided cutting biopsies, from carcinoid metastases of the liver, were taken before and after therapy with alpha-interferon. Each biopsy was examined under light microscopy and the amount of tumor tissue and connective tissue was quantified and then correlated to objective response to interferon therapy. A significant reduction of the amount of tumor tissue, in spite of...

Nitrite anion has been demonstrated to be a prodrug of nitric oxide (NO) with positive effects on tissue ischemia/reperfusion injury, cytoprotection, and vasodilation. However, effects of nitrite anion therapy for ischemic tissue vascular remodeling during diabetes remain unknown. We examined whether sodium nitrite therapy altered ischemic revascularization in BKS-Lepr(db/db) mice subjected to ...

Tumor cells may be eliminated by increasing their temperature. This is achieved via photothermal therapy (PTT) penetrating the tumor tissue with near-infrared light and converting energy into heat using agents. Copper sulfide nanoparticles (CuS NPs) are commonly used as PTAs in PTT. In this review, we aimed to discuss synergism between PTT CuS NPs other therapies such chemotherapy, radiotherapy...

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental commencing before the age of 12 years and characterized by developmentally inappropriate inattention, hyperactivity, and/or impulsivity symptoms. Stimulants such as methylphenidate (MPH) are used first-line therapy for children with ADHD. Psychostimulants may be associated vascular problems. Raynaud’s phenomenon (RP) periph...

Hyaline cartilage is a vascular and neural tissue with scanty chondrocytes and limited regenerative ability. After some serious injuries of the cartilage, healing process will take place through the formation of fibrocartilage structures. Currently, tissue engineering and cell therapy are 2 interesting therapeutic fields dealing with regenerative medicine. In this regard, tissue&...

Abstract The dose analysis of Boron Neutron Capture Therapy (BNCT) on head cancer using the Particle and Heavy Ion Transport Code System (PHITS) has been carried out. purpose this study was determine rate received irradiation time required for therapy BNCT method. research conducted through a simulation approach. PHITS code used to design an epithermal neutron source derived from accelerator de...

oocyte, embryo and ovarian tissue cryopreservation are being increasingly proposed for fertility preservation among cancer patients undergoing therapy to enable them to have babies after the cancer is cured. embryo cryopreservation is not appropriate for single girls without any sperm partner and also because oocyte retrieval is an extended procedure, it is impossible in cases requiring immedia...