INTRODUCTION Blunt and penetrating liver injuries make up one‐third of all abdominal injuries, and 5% of all trauma admissions are due to injuries to this organ [1]. Additionally, the majority of blunt liver injuries stem from motor vehicle crashes (Moore 2004). Validated computational models of liver are useful for understanding injury to the liver from mechanical loading. It has been shown pr...

Electrospun scaffolds can find numerous applications, including biomedical; for example, tissue engineering. Poly-L-lactic acid is considered suitable these but its low-thermal stability and poor mechanical properties limit this polymer use. The aim of work to obtain a modulation the final characteristics such as fibers dimension, wettability, elasticity, resistance rupture through choice polym...

At the past, damaged tissue was removed from the body of patients. But now tissue regeneration using scaffolds and implants are used to repair the damaged tissue and organs. Besides of the mechanical properties of metallic biomaterials, they suffer from bioinertness. Using some surface treatment techniques, the bioactivity and also corrosion resistance of titanium implants could be improved. In...

Abstract Mechanical aspects play an important role in brain development, function, and disease. Therefore, continuum-mechanics-based computational models are a valuable tool to advance our understanding of mechanics-related physiological pathological processes the brain. Currently, mainly phenomenological material used predict behavior tissue numerically. The model parameters often lack physica...

There is a clinical need for better blood vessel substitutes, as current surgical procedures are limited by the availability of suitable autologous vessels and suboptimal behavior of synthetic grafts in small caliber arterial graft (<5  mm) applications. The aim of the present study was to compare the mechanical properties of arterial and venous tissue-engineered vascular constructs produced by...

The matrix of decellularized organ retains the three-dimensional architecture and biochemical composition, as well as the original tissue microvasculature. This propertie make the decellularized lung very promising for the generation of functional bioartificial organs. This study aims to describe an experimental animal model that allows to analyze the behavior of the mechanical properties of de...

To keep the mechanical integrity of an organism it seems obvious that cells, as the building blocks, must be solid. Although it is clear that switching to a fluid would be catastrophic for organization of the body, it turns out that living cells do change their mechanical properties to a more fluid-like behavior when it comes to migration and force generation. Being fluid-like allows cells to a...