BACKGROUND/AIM Switching the patient from one pharmaceutical formulation of the same drug to another, may lead to therapeutic inadequancy in some cases. To minimize the risk, careful pharmacokinetic studies are desired in the pre-registration period and afterwards. METHODS A randomized, crossover design with one-week wash-out period between each dose was applied. Serum samples, obtained befor...

In this in vitro study, we investigated the efficacy of sodium hypochlorite (NaOCl) and calcium hydroxide (Ca(OH)2) in dissolving necrotic tissue and cleaning root canals. In the first part of the study, 0.5% NaOCl solution and Ca(OH)2 paste and solution were tested with samples of necrotic bovine muscle in different treatment modes and for different periods. The necrotic tissue was weighed bef...

Blue native gel electrophoresis (BN-PAGE) is used extensively for characterization of mitochondrial respiratory complexes and uses the binding of Coomassie brilliant blue G-250 to visualize proteins. Oxidative modification of sulfhydryl groups of such proteins can be evaluated by labeling with iodoacetamide conjugated to biotin (BIAM) and detected with streptavidin peroxidase on Western blots f...

Implantation of silicon wafers with Ga and P, under specific conditions, results in enhanced category-II (end of range) dislocation loop elimination after short thermal cycling. Comparison of these results with transmission electron microscopy studies of Si-, Ge-, As-, AI-, and Sb-implanted samples indicate that the enhanced elimination process occurs only when the peak of the impurity concentr...

A reactive fluid dissolving a uniform porous material triggers an instability in the dissolution front, leading to spontaneous formation of pronounced well-spaced channels in the surrounding rock matrix. The concentration field within the dissolving region contains two different length scales, upstream (no reaction) and downstream of the front position. Previous investigations of the reaction-i...

Enzymatic treatment of different sulphite pulps with cellulases has been studied in this work. Endoglucanases were shown to beneficially alter the properties of both paper-grade and dissolving-grade pulps. In the case of the paper-grade pulp, the treatment with endoglucanase resulted in a considerable reduction of the pulp refining time without decrease in strength properties. While for the dis...

This paper looks at the use of techniques to prevent the communication of steganographic data by filtering. These filters are broken into two categories; Overwriting and Dissolving. Overwriting can be defined as being the effective implementation of a Steganographic message over the original message. Dissolving can be defined as being modifications to the picture in order to prevent the decodi...

By modeling mass transfer phenomena, we simulate solids and liquids dissolving or changing to other substances. We also deal with the very small-scale phenomena that occur when a fluid spreads out at the interface of another fluid. We model the pressure at the interfaces between fluids with Darcy’s Law and represent the viscous fingering phenomenon in which a fluid interface spreads out with a ...

Articular cartilage, the load-bearing tissue of the joint, has limited repair and regeneration ability. The scarcity of treatment modalities for large chondral defects has motivated researchers to engineer cartilage tissue constructs that can meet the functional demands of this tissue in vivo. Cartilage tissue engineering requires 3 components: cells, scaffold, and environment. ...