this work reports a facile sonochemical route in the synthesis of nano particle of deferasirox for the first time. one application of nanotechnology is in improvement of available treatments for various diseases. deferasirox (icl670 or exjade) is a tridentate chelating agent for removing transfusion overload iron in thalassemia patients. in the present work, deferasirox was prepared in nano size...

objective: because of functional impairment caused by generalized anxiety disorder and due to cognitive side ‎effects of many anti-anxiety agents, in this study we aimed to evaluate the influence of passion ‎flower standardized extract on reaction time in patients with generalized anxiety disorder.‎ method: thirty patients aged 18 to 50 years of age, who were diagnosed with generalized anxiety ...

conclusions in conclusion, the prevalence of hcv genotype 1 was 51.7%, which was lower than the rates reported in other studies in turkey, while the prevalence of hcv genotype 3 was 46%, which was remarkably higher than the reported turkish data. in addition, the prevalence rate for genotype 3 reported in the present study is the highest that has ever been reported in the literature. results th...

conclusions findings of the present study showed that hcv genotype 3 was the predominant genotype followed by the subtypes 1a and 1b in yazd, central province of iran. in addition, there was no difference between hcv load and genotypes 1 and 3. hcv genotyping is recommended in other provinces of iran. objectives the main aim of this study was to estimate the prevalence of hcv genotypes in yazd,...

background: discovery of short cell free fetal dna (cffdna) fragments in maternal plasma has created major changes in the field of prenatal diagnosis. the use of cffdna to set up noninvasive prenatal test is limited due to the low concentration of fetal dna in maternal plasma therefore, employing a high efficiency extraction method leads to more accurate results. the aim of this study was to ev...

background: bordetella pertussis is the causative agent of pertussis. in brazil, laboratory diagnosis of pertussis is based on the culture. in 2010, was standardized the real-time pcr taqman® in routine diagnosis. objectives: the aim of this study was to evaluate the impact achieved with the introduction of rt-pcr for the routine diagnosis of pertussis and to compare with the results obtained f...

background: myofascial pain syndrome is a significant source of mechanical pain. the aim of this study was to investigate the effects of arm movement on reaction time in females with latent and active upper trapezius myofascial trigger point. methods: in this interventional study, a convenience sample of fifteen women with one active mtp, fifteen women with one latent mtp in the upper trapezius...

background advanced ambulance service (emergency medical services/ems) is considered to be an integral part of emergency medical care as the first assets responding to emergencies and disasters in the prehospital setting in most developed countries. objectives the aim of this study was to evaluate the current situation of shiraz’s ems by comparing data obtained during two different time periods...