UNLABELLED Ranaviruses (Iridoviridae) are posing an increasing threat to amphibian populations, with anuran tadpoles being particularly susceptible to these viral infections. Moreover, amphibians are the most basal phylogenetic class of vertebrates known to possess both type I and type III interferon (IFN)-mediated immunity. Moreover, little is known regarding the respective roles of the IFN me...

In eggs of Xenopus laevis, dorsal development is activated on the future dorsal side by cortical rotation, after fertilization. The immediate effect of cortical rotation is probably the transport of a dorsal determinant from the vegetal pole to the equatorial region on the future dorsal side. However, the identity and action of the dorsal determinant remain problematic. In the present experimen...

International trade of the invasive South African clawed frog (Xenopus laevis), a subclinical carrier of the fungal pathogen Batrachochytrium dendrobatis (Bd) has been proposed as a major means of introduction of Bd into naïve, susceptible amphibian populations. The historical presence of Bd in the indigenous African population of Xenopus is well documented. However, there are no reports docume...

A current trend in drug research is the desire to obtain novel antimicrobials with plant origins as an alternative therapy and a means curb antimicrobial resistance. This study evaluated phytochemistry antibacterial activity of ethyl acetate leaf extract Newbouldia laevis. The laevis was cold extracted Ethyl acetate. for it phytochemical constituents using standard methods effect against some c...

PURPOSE Prominin is a family of pentaspan transmembrane glycoproteins. They are expressed in various types of cells, including many stem/progenitor cells. Prominin-1 plays an important role in generating and maintaining the structure of the photoreceptors. In this study, we identified three prominin homologs in Xenopus laevis, a model animal widely used in vision research, and characterized the...

In a research paper entitled: Intracellular expression profi les measured by real-time PCR tomography in the Xenopus laevis oocyte, Dr. Kubista and fellow researchers describe a new method for measuring localized RNA expression profi les within single cells. Th e method is demostrated by using real-time PCR tomography to slice the Xenopus laevis (African Clawed Frog) oocyte into thin layers and...

Fragments of amplified Xenopus laevis DNA, coding for 18S and 28S ribosomal RNA and generated by EcoRI restriction endonuclease, have been linked in vitro to the bacterial plasmid pSC101; and the recombinant molecular species have been introduced into E. coli by transformation. These recombinant plasmids, containing both eukaryotic and prokaryotic DNA, replicate stably in E. coli. RNA isolated ...