Bisphosphonates are established as supportive therapy to reduce the frequency and severity of cancer-related skeletal complications. Oral formulations are preferred over intravenous if the patients are not hospitalized. The maximum absorption of oral bisphosphonates takes place in stomach. The adverse events with oral dosing are seen in buccal mucosa and gastrointestinal tract, which lead to po...

We introduce a composite tracer for the marine system, Alk, that has a global distribution primarily determined by CaCO3 precipitation and dissolution. Alk ∗ is also affected by riverine alkalinity from dissolved terrestrial carbonate minerals. We estimate that the Arctic receives approximately twice the riverine alkalinity per unit area as the Atlantic, and 8 times that of the other oceans. Ri...

Long-term reactivity and permeability are critical factors in the performance of granular iron permeable reactive barriers (PRBs). Thus it is a topic of great practical importance, as well as scientific interest. In this study, four types of source solutions (distilled H2O, 10 mg/L TCE, 300 mg/L CaCO3, and 10 mg/L TCE + 300 mg/L CaCO3) were supplied to four columns containing a commercial granu...

We have studied the formation and carried out an in vivo evaluation of carbonate apatite (CO3-Ap) and CO3-Ap/CaCO3 composite coatings on titanium substrates using the thermal substrate method. The coatings were formed on commercial pure titanium rods (diameter = 2mm, length = 5mm) and plates (thickness = 0.3mm) by the thermal substrate method in an aqueous solution that contained Ca(H2PO4)2, Ca...

OBJECTIVE To assess serum calcium, phosphorus and PTH levels with reference to K/DOQI targets in haemodialysis patients at Rawalpindi. Further more efficacy of calcium carbonate (CaCO3) was compared with calcium acetate (CaAc) for maintaining serum P and Ca levels in our ESRD patients. METHODS One hundred and ninety patients on haemodialysis receiving calcium phosphate binders (CaCO3 n = 128 ...

Lignocellulosic biomass is an economical and renewable feedstock for microbial production of bulk chemicals such as lactic acid. In many cases, simultaneous saccharification and fermentation (SSF) can achieve lower cost and higher productivity than the classical double step fermentation. Thus, in the present study, bagasse sulfite pulp was directly employed to produce lactic acid by SSF, using ...

Polyketide secondary metabolites share common precursor pools, acyl-CoA. Thus, the effects of engineering strategies for heterologous and native secondary metabolite production are often determined by the measurement of pikromycin in Streptomyces venezuelae. It is hard to compare the effectiveness of engineering targets among published data owing to the different pikromycin production media use...

[1] A new mechanism is proposed to explain the 100,000-year timescale for variations in Antarctic temperatures and atmospheric CO2 over the last 650,000 years. It starts with fluctuations in the oceanic overturning around Antarctica that release CO2 up to the atmosphere or trap it in the deep ocean. Every 50,000 years one of these fluctuations coincides with a changeover in the burial of CaCO3 ...

Latest advances of ionic liquids (ILs) have allowed to a new application on the dissolution calcium carbonate (CaCO3) scales where CaCO3 scale deposition seriously severe threat in petroleum field. In this study, molecular interaction between and ILs n-pyridinium chloride [NPy][Cl] was studied experimentally order get better understanding during scale. NMR FTIR spectroscopy used study solution ...