Abstract The Beijing-Tianjin-Hebei region, with the capital Beijing as core, carries a profound geo-culture and gathers numerous intangible cultural heritages. Studying spatial distribution characteristics influencing factors of heritage can help to propose positive suggestions for protection development from perspective sustainable development. Taking 329 national heritages in Beijing-Tianjin—...

Unique Genomic Arrangements in an Invasive Serotype M23 strain of Streptococcus pyogenes 1 Identify Genes that Induce Hypervirulence 2 3 Yunjuan Bao, Zhong Liang, a* Claire Booyjzsen, Jeffrey A. Mayfield, Yang Li, Shaun W. 4 Lee, Victoria A. Ploplis, Hui Song, Francis J. Castellino 5 6 * Co-first authors, contributed equally to the work. 7 8 The W.M. Keck Center for Transgene Research and Depar...

This study examines the acoustic realization of neutral tone in Tianjin Mandarin, which shows great variability in the f0 patterns. Previous studies, mainly with impressionistic data, have proposed that the neutral tone in Tianjin Mandarin has different underlying tonal targets depending on the tonal contexts, in particular the following tone. This presents a great challenge to the crossdialect...

Currently, Haze is one of the greatest environmental problems with serious impacts on human health in China, especially in capital region (Beijing-Tianjin-Hebei region). To alleviate this problem, the Chinese government introduced a National Air Pollution Control Action Plan (NAPCAP) with air pollutants reduction targets by 2017. However, there is doubt whether these targets can be achieved onc...

In order to measure the value of high-speed railway in development Beijing-Tianjin-Hebei urban agglomeration and provide empirical support for rationality “eight horizontal eight vertical” planning, based on impact mechanism economic growth, this paper uses data 13 prefecture level cities from 2009 2017 quantitatively study economy triggered by Growth effect. The results show that overall effec...

This paper selected panel data of Beijing-Tianjin-Hebei and other eastern regions except Beijing- Tianjin-Hebei from 1999 to 2018. The economic convergence model, double difference method twoway fixed effect model are used study the influence coordinated development strategy on regional convergence. It is found that (1) has a negative growth as whole, Tianjin city Hebei province, positive Beiji...

Bone metastasis affects more than 70% of advanced breast cancer patients, but the molecular mechanisms of this process remain unclear. Here, we present clinical and experimental evidence to clarify the role of the integrin b-like 1 (ITGBL1) as a key contributor to bone metastasis of breast cancer. In an in vivo model system and in vitro experiments, ITGBL1 expression promoted formation of osteo...

The purpose of this design is to carry on the reconstruction planning present Baimiao passenger station, in order improve its flow and service quality, residents' travel experience. In paper, volume Tianjin from 2010 2019 taken as research object, Passenger Station predicted by exponential smoothing method 2021 2028. Then, according proportion total Tianjin. Then make reasonable for station.. F...

the “driving force - pressure - state - impact – response” modeling framework isadopted to consider the formation mechanisms of environmental risks and the requirements ofecological environment protection. moreover, a systematical index system and evaluation model forthe measurement of the coastal ecological security level is put forward in this paper to assess thestate of coastal ecological en...