BACKGROUND Hashimoto's thyroiditis is the most common endocrinopathy in premenopausal women, and is associated with various gynecological problems, including recurrent miscarriage and unexplained infertility. A possible influence of Hashimoto's thyroiditis on the success of intrauterine insemination seems likely, but has not been evaluated as yet. Therefore, the aim of our study was to retrospe...

The prevalence of thyroid diseases including autoimmune hyperthyroidism (Graves’ disease), thyroiditis, and different forms cancer is increasing every year, while the effectiveness their treatment remains low limited, mainly, to replacement therapy with hormones surgical radioisotope methods. This review presents current state problem pharmacological correction in new approaches regulation func...

The effects of thyroid stimulating hormone (TSH) deficiency on thyroid development was examined using ultrasonography in a child with congenital isolated TSH deficiency. Ultrasound revealed the thyroid gland was one sixth normal volume, suggesting that TSH plays an important part in thyroid growth, but not a critical role in differentiation.

ing hormone and follicle stimulating hormone with a low oestradiol concentration confirm menopausal status. In peri­ menopause, some menstrual bleeding may still be occurring, and luteinising hormone, follicle stimulating hormone and oestradiol may be normal, or only follicle stimulating hor­ mone may be raised. If there is any doubt about perimeno­ pausal status, blood tests should be repeated...

Melatonin is an indoleamine with multiple functions in both plant and animal species. In addition to data in literature describing many other important roles for melatonin, such as antioxidant, circadian rhythm controlling, anti-aging, antiproliferative or immunomodulatory activities, our group recently reported that thyroid C-cells synthesize melatonin and suggested a paracrine role for this m...

The occurrence of thyroid tumors induced by N-methyl-N-nitrosourea (MNU) and low iodine diet in Long-Evans (LE) rats was studied with special reference to sex difference, effect of gonadectomy, and estradiol administration. Rats of experimental groups 1-6 were given i.v. injections of 40 mg of MNU/kg of body weight at 50 days of age and fed on low iodine diet from 28 days of age to the end of t...

Thyroiditis should be in the differential for hyperthyroidism when thyroid-stimulating hormone (TSH) is suppressed and T3/T4 levels are elevated. Suspicion of further increased patient can exhibit symptoms such as weight loss, anxiety, feeling feverish, tremors, shaking, sweating. Hyperthyroidism generally classified being overt or subclinical. In following case, had which considered more sever...

The occurrence of thyroid tumors induced by A'-methyl-A'-nitrosourea (MM ) and low iodine diet in Long-Evans (LE) rats was studied with special reference to sex difference, effect of gonadectomy, and estradiol administration. Rats of experimental groups 1-6 were given i. v. injections of 40 mg of MNU/kg of body weight at SO days of age and fed on low iodine diet from 28 days of age to the end o...

The thyrotropin receptor (TSHR) is a seven transmembrane G-protein linked glycoprotein expressed on the thyroid cell surface and which, under the regulation of TSH, controls the production and secretion of thyroid hormone from the thyroid gland. This membrane protein is also a major target antigen in the autoimmune thyroid diseases. In Graves' disease, autoantibodies to the TSHR (TSHR-Abs) stim...

THYROSTIMULIN, BUT NOT THYROID-STIMULATING HORMONE, ACTS AS A PARACRINE REGULATOR TO ACTIVATE THYROID-STIMULATING HORMONE RECEPTOR IN THE MAMMALIAN OVARY Su-Chin Sun, Pei-Jen Hsu, Fang-Ju Wu, Sheng-Hsiang Li, Chung-Hao Lu and Ching-Wei Luo Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan. Department of Medical Research, Mackay Memorial ...