We measured total and regional cerebral blood flow (CBF, rCBF) and cerebral metabolic rate (CMR) of oxygen (O2), glucose (G), and lactate (L) levels for 4 h after 16 min global brain ischemia in rhesus monkeys with and without post-insult thiopental therapy. Eleven monkeys weighing 4-5 kg anesthetized with 1 percent halothane, 66 percent nitrous oxide and 33 percent oxygen, were subjected to 16...

BACKGROUND Most of what is known regarding the actions of injectable barbiturate anesthetics on the activity of lumbar sensory neurons arises from experiments performed in acute animal preparations that are exposed to invasive surgery and neural depression caused by coadministered inhalational anesthetics. Other parameters such as cortical synchronization and motor ouflow are typically not moni...

This retrospective study was designed to compare the cost of anesthesia in three different groups of patients who received general anesthesia for a diagnostic dilatation and curettage procedure. The analysis included 194 patients, ASA physical status I, II, or III. All patients were outpatients with similar body mass index and age. The three groups were thiopental/isoflurane (n = 13), propofol/...

BACKGROUND Pulmonary surfactant is a complex mixture of proteins and phospholipids synthetized by alveolar type II cells. Volatile anesthetics have been shown to reduce surfactant phospholipid biosynthesis by rat alveolar type II cells. Surfactant-associated protein C (SP-C) is critical for the alveolar surfactant functions. Our goal was to evaluate the effects of halothane and thiopental on SP...

Objectives: This study aimed to examine the effects of orally administered metoprolol on frequency and severity pain caused by rocuronium injection in patients who started use were currently using oral for any reason such as ischemic heart disease, hypertension, arrhythmias. Methods: Patients evaluated four groups. Group M: did not receive lidocaine before application rocuronium. ML: received a...

UNLABELLED The prediction of seizure thresholds in electroconvulsive therapy (ECT) remains problematic. We examined the relationship between bispectral index (BIS) score and seizure duration in ECT performed under thiopental anesthesia in patients receiving their usual regimen of antidepressant medication for its potential as a predictor of seizure inducibility. One-hundred ECT treatments were ...

Epidural analgesia is an effective technique to treat acute and chronic pain as well as to provide preemptive, intraoperative, and postoperative analgesia. This study was performed to evaluate the effects of epidurally injected morphine and a control group that received 0.9% sodium chloride. Eighteen healthy male adult ponies were studied. Two groups of 9 were formed. Group M (morphine) receive...