A simple and sensitive method based on liquid chromatography-atmospheric pressure ionization-mass spectrometry is described for the determination of 4 benzimidazole pesticides (carbendazim, thiabendazole, benomyl, and thiophanate-methyl) and imidacloprid in vegetables and fruits. Food samples were typically extracted with ethyl acetate to draw the analytes into the organic phase. No cleanup ste...

A 65-year-old man with steroid-dependent chronic airflow obstruction presented with progressive dyspnea and weight loss. Travel history included a military tour in southeast Asia. A chest roentgenogram revealed hyperexpanded lung fields with diffusely increased interstitial markings. The Papanicolaou stain of expectorated sputum demonstrated the rhabditiform larvae of Strongyloides stercoralis....

Schizosaccharomyces pombe Mst1 is a member of the MYST family of histone acetyltransferases and is the likely ortholog of Saccharomyces cerevisiae Esa1 and human Tip60 (KAT5). We have isolated a temperature-sensitive allele of this essential gene. mst1 cells show a pleiotropic phenotype at the restrictive temperature. They are sensitive to a variety of DNA-damaging agents and to the spindle poi...

The use of veterinary drugs may cause the presence of residues in food of animal origin if appropriate withdrawal periods are not respected. A high-performance liquid chromatography (HPLC) method has been developed for the simultaneous detection of 11 benzimidazole residues, including metabolites – albendazole, albendazole sulphoxide, albendazole sulphone, fenbendazole, fenbendazole sulphoxide ...

Mice, frogs, and even yeast are useful in research in large part because they share so many of our genes. And as a surge of genetic data has become available in recent years, scientists have realized that not just individual genes but entire genetic pathways are often conserved across disparate organisms. In some cases, a genetic module doesn’t serve an identical purpose across species; rather,...

Polyarteritis nodosa (PAN), a systemic necrotising vasculitis that affects medium- and small-sized arteries, has visceral involvement in 40-60% of the patients. According to the Five-Factor Score (FFS), it is associated with poor outcome. We describe a patient who underwent orthotopic liver transplantation (OLT) for severe ductopenia induced by thiabendazole that was empirically prescribed for ...

Regular monitoring of benzimidazole resistance status helps in timely implementation of resistance mitigation strategies in farms. Egg hatch assay (EHA) evaluates the ability of benzimidazoles to inhibit or prevent embryonation and hatching of nematode eggs and is the standard in vitro test for detection of benzimidazole resistance. The present study reports detection of benzimidazole resistanc...

See related article on page 126 The article by Figueiredo et al.,1 published in the current issue of Jornal de Pediatria, provides important information about clinical and epidemiological investigation into toxocariasis in the pediatric population. The study analyzes the association of Toxocara canis infection with some variables, such as asthma, cough, recurrent pneumonia, hepatomegaly, and eo...