393 a Assistant Professor, İnönü University, Faculty of Dentistry, Department of Orthodontics, Malatya, Turkey. b Associate Professor, c Assistant Professor, Cumhuriyet University, Faculty of Dentistry, Department of Orthodontics, Sivas, Turkey. d Assistant Professor, Cumhuriyet University, Faculty of Dentistry, Department of Endodontics, Sivas, Turkey. Corresponding author: Fırat Öztürk. İnönü...

We address the need for affordable, rapid, and easy to use diagnostic technologies by coupling an innovative thermocycling system that harnesses natural convection to perform rapid DNA amplification via the polymerase chain reaction (PCR) with smartphone-based detection. Our approach offers an inherently simple design that enables PCR to be completed in 10-20 minutes. Electrical power requireme...

This study used real-time PCR assays to screen small sample volumes for a comprehensive range of 35 respiratory pathogens. Initial thermocycling was limited to 20 cycles to avoid competition for reagents, followed by a secondary real-time multiplex PCR. Supplementary semi-nested human metapneumovirus and picornavirus PCR assays were required to complete the acute respiratory pathogen profile. P...

Microfluidic devices are a promising new tool for studying and optimizing (bio)chemical reactions and analyses. Many (bio)chemical reactions require accurate temperature control, such as for example thermocycling for PCR. Here, a new integrated temperature control system for microfluidic devices is presented, using chemical and physical processes to locally regulate temperature. In demonstratio...